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'This gives hope': A third COVID-19 vaccine dose can boost protection for organ transplant recipients | Science


Science’s COVID-19 reporting is supported by the Heising-Simons Foundation.
A few months ago, transplant surgeon Dorry Segev was despondent about how COVID-19 vaccines were performing in patients like his, who have a donated organ and take powerful drugs to suppress their immune system. After one dose of a highly effective messenger RNA (mRNA) vaccine, for example, just 17% of those patients churned out protective antibodies against the pandemic coronavirus, and after the standard two doses, only 54% did. The very medications his patients took to protect their transplanted organ precluded them from mounting a healthy immune response after the vaccine. Even people who did make the antiviral antibodies often had very low levels, raising questions about how well they were shielded from COVID-19. ....

United States , Leif Erik Sander , Jennifer Couzin Frankel , Salomon Stemmer , Deepali Kumar , Sophie Ohlmann , Ravi Parikh , Heising Simons Foundation , Johns Hopkins University , Strasbourg University Hospital , National Institutes Of Health , University Hospital , University Of Pennsylvania , Tel Aviv University , Dorry Segev , Although Segev , Toronto General , National Institutes , Cancer Cell , ஒன்றுபட்டது மாநிலங்களில் , லீஃப் ஏறிக் சாண்டர் , தீபாளி குமார் , ரவி பாறிக் , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் , ஸ்ட்ராஸ்பர்க் பல்கலைக்கழகம் மருத்துவமனை , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் ,