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New York state ends stem cell research funding


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Projects funded by the New York State Stem Cell Science program included ones studying human embryonic stem cells (center).
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New York state ends stem cell research funding
Apr. 16, 2021 , 3:45 PM
Over the past decade, New York state has become an international hub of stem cell research. In part, that’s thanks to one of the United States’s only state-level programs devoted exclusively to this area of science, researchers say. But now, New York’s state government has killed the program, which scientists fear will slow research progress and cause a brain drain to other states and countries. ....

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In Triculture Model, Astrocyte-Microglia Cross Talk Spurs Inflammation


16 Feb 2021
In the brain, complex interactions between different cell types can drive inflammation and disease. This cross talk is hard to study in vitro, because culture systems are often too simple to recapitulate the intricacies of the brain, or the mix of cells is too poorly defined to give reliable results. In the February 8 Nature Neuroscience, researchers led by Lorenz Studer at the Sloan Kettering Institute for Cancer Research in New York City describe a triculture system of neurons, microglia, and astrocytes that combines pure populations of each cell type in a defined ratio. Generated from human pluripotent stem cells, each cell type can be genetically manipulated. Because the cells can be frozen in large quantities, the cultures can be readily scaled up as well. ....

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BlueRock Therapeutics in Collaboration with Memorial Sloan Kettering Cancer Center Receives IND Clearance for DA01 in Parkinson's Disease


BlueRock Therapeutics in Collaboration with Memorial Sloan Kettering Cancer Center Receives IND Clearance for DA01 in Parkinson s Disease
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CAMBRIDGE, Mass., Jan. 7, 2021 /PRNewswire/ BlueRock Therapeutics, a preclinical stage biopharmaceutical company and wholly-owned subsidiary of Bayer AG, in collaboration with Memorial Sloan Kettering Cancer Center (MSK), announced today that the U.S. Food and Drug Administration (FDA) has cleared their Investigational New Drug (IND) application to proceed with a Phase 1 (Ph1) study in patients with advanced Parkinson s disease (PD). This is the first trial in the United States to study pluripotent stem cell-derived dopaminergic neurons in patients with Parkinson s disease. Under the IND, BlueRock and MSK will execute a Ph1 clinical trial to evaluate the safety, tolerability and preliminary efficacy of DA01 in patients with PD.  ....

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Leaders in stem cell research chart the next decade of breakthroughs at ISSCR's VISION2030


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Skokie, IL - The ISSCR is bringing together successful biotech CEOs who have transformed scientific breakthroughs into thriving businesses that are improving human health into one program 7-8 January 2021.
VISION2030 comes at a pivotal moment in regenerative medicine and stem cell science as discovery, translation, and investment intersect.
Thursday, 7 January
STEMCELL Technologies Executive Interview
Interviewed by ISSCR Board Member Valentina Greco, Yale University School of Medicine, USA
STEMCELL Technologies mission is to advance the pursuit of scientific knowledge by supplying high quality, innovative reagents, tools, and services that enable life science research.
Surrozen Executive Interview
Claudia Janda, Princes Máxima Centrum, Netherlands l Surrozen Founder ....

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