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Environmental News Network - Green Tea Compound Aids Tumor-Suppressing, DNA-Repairing Protein


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An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy cancerous cells.
An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy cancerous cells. Published today in Nature Communications, a study of the direct interaction between p53 and the green tea compound, epigallocatechin gallate (EGCG), points to a new target for cancer drug discovery.
“Both p53 and EGCG molecules are extremely interesting. Mutations in p53 are found in over 50% of human cancer, while EGCG is the major anti-oxidant in green tea, a popular beverage worldwide,” said Chunyu Wang, corresponding author and a professor of biological sciences at Rensselaer Polytechnic Institute. “Now we find that there is a previously unknown, direc ....

Chunyu Wang , Nature Communications , Rensselaer Polytechnic Institute , Rensselaer Center , Rensselaer Polytechnic , Interdisciplinary Studies , Environmental News , Environmental Policy , Climate Change , Green Building , இயற்கை தகவல்தொடர்புகள் , ரென்சீலர் பாலிடெக்நிக் நிறுவனம் , ரென்சீலர் மையம் , ரென்சீலர் பாலிடெக்நிக் , இடைநிலை ஆய்வுகள் , சுற்றுச்சூழல் செய்தி , சுற்றுச்சூழல் பாலிஸீ , சுற்றுச்சூழல் அமைப்பு , காலநிலை மாற்றம் , பச்சை கட்டிடம் ,

Antioxidant Found in Green Tea May Increase Levels of p53


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An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy cancerous cells. Published today in Nature Communications, a study of the direct interaction between p53 and the green tea compound, epigallocatechin gallate (EGCG), points to a new target for cancer drug discovery.
“Both p53 and EGCG molecules are extremely interesting. Mutations in p53 are found in over 50% of human cancer, while EGCG is the major anti-oxidant in green tea, a popular beverage worldwide,” said Chunyu Wang, corresponding author and a professor of biological sciences at Rensselaer Polytechnic Institute. “Now we find that there is a previously unknown, direct interaction between the two, which points to a new path for developing anti-cancer drugs. Our work helps to explain how EGCG is able to boost p53’s anti-cancer activity, opening the do ....

Jing Zhao , United States , University Of Massachusetts , Lauren Gandy , Yingkai Zhang , Curt Breneman , Jianhan Chen , Chunyu Wang , Weihua Jin , Sozanne Solmaz , Xinyue Liu , Stewart Loh , Michael Cosgrove , Yuanyuan Xiao , Alan Blaney , Lufeng Yan , Nature Communications , University Massachusetts , Merck Research Laboratories , Binghamton University , National Institutes Of Health , Rensselaer Polytechnic Institute , Rensselaer School Of Science , Rensselaer Center , China Agricultural University , York University ,

Major antioxidant in green tea may increase levels of natural anti-cancer protein


Major antioxidant in green tea may increase levels of natural anti-cancer protein
An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the guardian of the genome for its ability to repair DNA damage or destroy cancerous cells. Published today in
Nature Communications, a study of the direct interaction between p53 and the green tea compound, epigallocatechin gallate (EGCG), points to a new target for cancer drug discovery.
Both p53 and EGCG molecules are extremely interesting. Mutations in p53 are found in over 50% of human cancer, while EGCG is the major anti-oxidant in green tea, a popular beverage worldwide. Now we find that there is a previously unknown, direct interaction between the two, which points to a new path for developing anti-cancer drugs. Our work helps to explain how EGCG is able to boost p53 s anti-cancer activity, opening the door to developing drugs with EGCG-like compounds. ....

Jing Zhao , Lauren Gandy , Chunyu Wang , Weihua Jin , Emily Henderson , Xinyue Liu , Yuanyuan Xiao , Lufeng Yan , Alan Blaney , Nature Communications , Merck Research Laboratories , National Institutes Of Health , Rensselaer Polytechnic Institute , Rensselaer Center , China Agricultural University , Professor Of Biological Sciences , University Of Massachusetts , University Of New York At Binghamton , York University , Corresponding Author , Biological Sciences , Rensselaer Polytechnic , Interdisciplinary Studies , Intrinsically Disorderedn Terminal Domain , National Institutes , Upstate Medical ,

Green tea compound aids tumour-suppressing

Green tea compound aids tumour-suppressing
ohiostandard.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ohiostandard.com Daily Mail and Mail on Sunday newspapers.

State University Of New York At Binghamton , New York , United States , Rensselaer Polytechnic Institute , New York University , Jing Zhao , Lauren Gandy , Curt Breneman , Chunyu Wang , Weihua Jin , Xinyue Liu , Yuanyuan Xiao , Lufeng Yan , Alan Blaney , Nature Communications , Merck Research Laboratories , National Institutes Of Health , Rensselaer School Of Science , Rensselaer Center , China Agricultural University , University Of Massachusetts , University Of New York At Binghamton , York University , Rensselaer Polytechnic , Interdisciplinary Studies , Rensselaer School ,

Study reveals green tea compound aids tumour-suppressing, DNA-repairing protein

New York [US], February 13 (ANI): An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the 'guardian of the genome' for its ability to repair DNA damage or destroy cancerous cells. ....

State University Of New York At Binghamton , New York , United States , Rensselaer Polytechnic Institute , New York University , Jing Zhao , Lauren Gandy , Curt Breneman , Chunyu Wang , Weihua Jin , Xinyue Liu , Yuanyuan Xiao , Lufeng Yan , Alan Blaney , Nature Communications , Merck Research Laboratories , National Institutes Of Health , Rensselaer School Of Science , Rensselaer Center , China Agricultural University , University Of Massachusetts , University Of New York At Binghamton , York University , Rensselaer Polytechnic , Interdisciplinary Studies , Rensselaer School ,