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U.S. health officials are investigating reports that Moderna Inc's COVID-19 vaccine may be linked to a higher risk of a rare heart condition in younger adults than previously thought, the Washington Post reported late on Thursday, citing people familiar with the review. ....
Parkinson’s disease (PD) is the second most neurodegenerative disease in the world. T cell infiltration in the central nervous system (CNS) has provided insights that the peripheral immune cells participate in the pathogenesis of PD. However, the association between the peripheral immune system and CNS is remained to be elucidated. Here, we analyzed an incorporative substantial nigra expression data as well as another blood expression data using the CIBERSORT to obtain the 22 immune cells fraction and then explored the molecular function to identify the potential key immune cell types and genes of PD. We observed the proportions of naïve CD4 T cells, gamma delta T cells, resting NK cells, neutrophils in the blood, and regulatory T cells (Tregs) in the substantial nigra were significantly different between PD patients and healthy controls (HC). We identified p53-induced death domain protein 1 (PIDD1) as the hub gene of a Parkinson’s disease-related module. The set of neuron-spe ....
The Indian drug regulator's subject expert committee has recommended emergency use approval for Zydus Cadila's three-dose COVID-19 vaccine, CNBC-TV18 reported on Friday, citing sources. ....
China is facing a high profile test of its commitment to curbing industrial pollution after steel output surged in the first half of the year to well beyond its target of capping production at 2020's peak, sending emissions to new highs. ....