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Invasive Approach Best for Cocaine-Linked NSTEMI, but DAPT Is Key


March 16, 2021
Patients with a history of cocaine use who present with non-ST-segment elevation myocardial infarction have a lower risk of future major adverse cardiovascular events if treated invasively rather than with a more-conservative approach, according to a new retrospective study.
Overall, invasive management, which included coronary angiography followed by PCI or CABG if needed, lowered the risk of MACE at 6 months by 28% compared with a noninvasive strategy.
The results, however, point to one of the major challenges in treating patients with cocaine-associated NSTEMI, namely their ability to adhere to posttreatment dual antiplatelet therapy (DAPT). While there was no greater risk of emergent revascularization in the overall cohort, that risk was significantly elevated among patients deemed nonadherent to medical therapy who’d been treated with a drug-eluting stent, report researchers. ....

El Paso , United States , Mehdi Shishehbor , Shilpkumar Arora , Debabrata Mukherjee , L Kristin Newby , Richard Lange , Md Texas Tech University Health Sciences Center , American Heart Association , American College Of Cardiology , Md Duke Clinical Research Institute , Case Western Reserve University School , Cardiovascular Interventions , Treatment Best , American College , Nationwide Readmissions Database , Duke Clinical Research Institute , Texas Tech University Health Sciences Center , எல் பாசோ , ஒன்றுபட்டது மாநிலங்களில் , தேவப்ரதா முகர்ஜி , ல் கிறிஸ்டின் புதியவர் , ரிச்சர்ட் லாங்கே , ம்ட் டெக்சாஸ் தொழில்நுட்பம் பல்கலைக்கழகம் ஆரோக்கியம் அறிவியல் மையம் , அமெரிக்கன் இதயம் சங்கம் , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் ,

CABANA Supports Use of AF Ablation in Patients With Heart Failure


February 12, 2021
Participants in the CABANA trial who had stable heart failure mostly with preserved ejection fraction in addition to atrial fibrillation (AF) at baseline fared better when they underwent catheter ablation than when they were started on medical therapy alone, a detailed subgroup analysis shows.
Those randomized to ablation had lower risks of mortality, the primary composite outcome of the trial (death, disabling stroke, serious bleeding, or cardiac arrest), and AF recurrence, as well as improved quality of life, according to researchers led by Douglas Packer, MD (Mayo Clinic Hospital St. Marys Campus, Rochester, MN), principal investigator for the trial. ....

Jonathan Piccini , Douglas Packer , Us National Institutes Of Health , Md Duke Clinical Research Institute , Mayo Clinic Hospital , Marys Campus , Duke Clinical Research Institute , Specific Symptom , டக்ளஸ் ப்யாகர் , எங்களுக்கு தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , ம்ட் டியூக் மருத்துவ ஆராய்ச்சி நிறுவனம் , மயோ சிகிச்சையகம் மருத்துவமனை , மேரிஸ் வளாகம் , டியூக் மருத்துவ ஆராய்ச்சி நிறுவனம் , குறிப்பிட்ட அறிகுறி ,