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GDMT With ARNI Linked to Less MR, May Obviate Need for Interventions

Before TEER or surgery, patients with MR should be optimized on GDMT with sacubitril/valsartan for at least 6 months, say experts.

United statesMitraclip abbottJamesl januzzi jrLos angelesGregg fonarowJames januzzi jrG michael felkerHeart failure society of americaMd university of californiaMd duke clinical research instituteMassachusetts general hospitalHeart failure societyDuke clinical research institute

GDMT With ARNI Lessens MR, Perhaps Obviating Need for Interventions

Before TEER or surgery, patients with MR should be optimized on GDMT with sacubitril/valsartan for at least 6 months, say experts.

United statesMitraclip abbottJamesl januzzi jrLos angelesGregg fonarowJames januzzi jrG michael felkerHeart failure society of americaMd university of californiaMd duke clinical research instituteMassachusetts general hospitalHeart failure societyDuke clinical research institute

GDMT With ARNI Lessens MR Severity, Potentially Obviating Need for Interventions

Before TEER or surgery, patients with MR should be optimized on GDMT with sacubitril/valsartan for at least 6 months, say experts.

United statesMitraclip abbottJamesl januzzi jrLos angelesGregg fonarowJames januzzi jrG michael felkerHeart failure society of americaMd university of californiaMd duke clinical research instituteMassachusetts general hospitalHeart failure societyDuke clinical research institute

Optimized HF Meds May Lessen MR Severity, Avoid Invasive Therapy

Patients with heart failure and mitral regurgitation should get at least 6 months of optimized guideline-directed medical therapy before invasive mitral repair is considered, researchers say.

United statesNorth carolinaDuke universityWindtree therapueticsJamesl januzziBristol myers squibbBristol myersG michael felkerAmerican heart associationBoehringer ingelheimNovartis pharmaceuticalsCardiovascular researchBlood instituteNational heartHarvard medical schoolGerman center

Vintage Drug Atop Loop Diuretics Boosts ADHF Decongestion: ADVOR

Adding the IV drug to loop diuretics in the ADVOR trial improved decongestion success in volume-overloaded patients with acute decompensated heart failure, researchers reported.

Region flamandeUniversity of texas southwestern medical centerUnited statesNorth carolinaDuke universityComunidad autonoma de catalunaWilfried mullensMarkh draznerBristol myers squibbG michael felkerEuropean society of cardiology congressDuke university school of medicineAbbott fundBelgian health care knowledge centerBoehringer ingelheimBoston scientific

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