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Microarchitecture and Insulin Responsiveness of Fat Cells Uncovered by Spatial Transcriptomics

Fat cells affect the body’s sensitivity to insulin. Applying an spatial transcriptomics approach, researchers at Karolinska Institute, Sweden, have discovered that there are 18 types of fat cells in white fat tissue including three different subtypes of mature fat cells only one of which responds to insulin. The findings may be relevant for future treatments of metabolic diseases such as insulin-resistant type 2 diabetes and obesity.

Only one human fat cell subtype responds to insulin stimulation

Only one human fat cell subtype responds to insulin stimulation
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