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Cancer discovery could revive failed treatments for solid tumors

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IMAGE: Research from UVA s Jogender Tushir-Singh, PhD, explains why the antibody approaches effectively killed cancer tumors in lab tests but proved ineffective in people.
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Credit: Dan Addison | UVA Communications
New research from UVA Cancer Center could rescue once-promising immunotherapies for treating solid cancer tumors, such as ovarian, colon and triple-negative breast cancer, that ultimately failed in human clinical trials.
The research from Jogender Tushir-Singh, PhD, explains why the antibody approaches effectively killed cancer tumors in lab tests but proved ineffective in people. He found that the approaches had an unintended effect on the human immune system that potentially disabled the immune response they sought to enhance. ....

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Researchers say they've made a discovery in a cancer treatment originally thought not to work

Researchers say theyâve made a discovery in a cancer treatment originally thought not to work
Cancer Center (FILE)
By Daniel Grimes | April 6, 2021 at 2:22 PM EDT - Updated April 6 at 2:22 PM
CHARLOTTESVILLE, Va. (WVIR) - Researchers at the University of Virginia Cancer Center say theyâve made a discovery that could revive a cancer treatment originally thought not to work.
It is an antibody treatment for solid cancer tumors like ovarian, colon, and triple negative breast cancers. Originally the treatment had an unintended effect, suppressing a personâs immune system in clinical trials.
Now researchers say theyâve figured out a way to make it work. ....

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The gender pay gap still exists and it isn't getting better

The gender pay gap still exists and it isn't getting better
kgw.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kgw.com Daily Mail and Mail on Sunday newspapers.

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'Each time we get a different answer': Do older children arriving to Canada have to stay in quarantine hotels?

A group of Toronto-area parents are struggling to interpret Canada’s rules over whether younger adults and older children have to book themselves into so-called quarantine hotels when they return to Canada.
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College wrestling: N.C. State wins third consecutive ACC team title with five champs

N.C. State takes home the conference title
Led by ACC champions Tariq Wilson, Hayden Hidlay, Daniel Bullard, Trent Hidlay, and Deonte Wilson, the N.C. State Wolfpack won their third consecutive ACC title. The Wolfpack came into the tournament as the No. 2 team in the conference after dropping a dual earlier in the year on criteria to the Virginia Tech Hokies, but Sunday night was all about the Pack.
The Hidlay brothers headlined the success of the team, with Hayden winning his fourth conference title in as many years and the younger Hidlay, Trent, winning his first title in sudden victory. Both will aim to carry this success into the 2021 NCAA tournament and chase their first national titles. ....

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