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Princess Margaret Cancer Centre Researchers Discover Key Stem Cell Dormancy Mechanism Which Could Help Unlock Future Cancer Treatments

Princess Margaret Cancer Centre Researchers Discover Key Stem Cell Dormancy Mechanism Which Could Help Unlock Future Cancer Treatments
newswise.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newswise.com Daily Mail and Mail on Sunday newspapers.

John Dick , Stephanie Xie , Laura Garcia Prat , University Health Network , University Of Toronto Medicine , Michener Institute For Education , Canadian Cancer Society , Princess Margaret Cancer Centre , Canada First Research Excellence Fund , Terry Fox New Frontiers Program , University Of Toronto , Princess Margaret Cancer Centre Foundation , International Development Research Centre , Canadian Institutes For Health Research , Ontario Institute For Cancer Research , Toronto Rehabilitation Institute , Princess Margaret , Cell Stem , University Health , Ontario Institute , Cancer Research , Canadian Institutes , Health Research , Term Fellowship , Benjamin Pearl Fellowship , Trillium Therapeutics ,

AI outperforms humans in creating cancer treatments, but do doctors trust it?

The impact of deploying Artificial Intelligence (AI) for radiation cancer therapy in a real-world clinical setting has been tested by Princess Margaret researchers in a unique study involving physicians and their patients. ....

Srinivas Raman , Charles Catton , Naghmeh Isfahanian , Tim Craig , Vickie Kong , Peter Chung , Andrew Bayley , Michaelc Tjong , Tom Purdie , Chris Mcintosh , Mary Gospodarowicz , Maria Madden , Joelle Helou , Padraig Warde , Leigh Conroy , Thomas Purdie , National Sciences , University Health Network , Princess Margaret Cancer Foundation , Michener Institute For Education , Engineering Research Council Of Canada , Canadian Institutes Of Health Research , Princess Margaret Cancer Centre , Techna Institute , University Of Toronto , Department Of Medical Imaging ,

Turning a pancreatic cancer cell's addiction into a death sentence

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IMAGE: Senior author and Princess Margaret Scientist Dr. Marianne Koritzinsky s research reveals the potential of targeted therapies to exploit unique metabolic features of pancreatic cancer cells.
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Credit: Visual Services, UHN
(Toronto, Friday, May 7, 2021) Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them.
Led by Princess Margaret Cancer Centre (PM) Scientist Dr. Marianne Koritzinsky, researchers showed that about half of patient-derived pancreatic cancer cell lines are highly dependent or addicted to the protein peroxiredoxin 4 (PRDX4), as a result of the altered metabolic state of the cancer cell. ....

United States , Alexandra Radkewycz , Marianne Koritzinsky , Pionyr Immunotherapeutics , Bradlyg Wouters , David Hedley , Jason Moffat , Paulc Boutros , University Health Network , Scientific Advisory Boards Of Biosymetrics Inc , Michener Institute For Education , Terry Fox Foundation Research Institute , Senior Public Affairs Advisor , University Of Toronto , American Association For The Advancement Of Science , Institute Of Medical Science , Ontario Ministry Of Health , Princess Margaret Cancer Centre Pm Scientist Dr , Donnelly Centre For Cellular , Toronto Rehabilitation Institute , Princess Margaret Cancer Foundation , Intersect Diagnostics Inc , Biomolecular Research , Princess Margaret Cancer Centre , Cancer Research Society Robert Letterman Memorial Fund , Science Advances ,

A Canadian success story: world-first to treat Fabry disease with gene therapy

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IMAGE: Darren Bidulka rests after his modified blood stem cells were transplanted into him at the Foothills Medical Centre in Calgary in 2017, allowing him to stop his enzyme therapy. (From.
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Credit: Courtesy of Darren Bidulka
(Thursday, Feb. 25, 2021, Toronto) Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.
The Canadian research team was the first to use gene therapy in 2017 to treat patients with Fabry disease, a rare, chronic illness that can damage major organs and shorten lives. They report their findings today in the journal ....

City Of , United Kingdom , Stephen Couban , Darren Bidulka , Aneal Khan , Michael West , Armand Keating , Christiane Auray Blais , Ryan Deveau , Anthony Rupar , Amicus Therapeutics , London Health Sciences Centre , University Health Network , Nature Communications , Michener Institute For Education , Alberta Health Services , Takeda Pharmaceuticals , University Of Toronto , Fund Professor , Kidney Foundation Of Canada , Avrobio Inc , Alberta Children Hospital Research Institute , Toronto Rehabilitation Institute , Cumming School Of Medicine , Alberta Health Service Foothills Medical Centre , Senior Scientist At Princess Margaret Cancer Centre ,

A Canadian success story: world-first to treat Fabry disease with gene therapy

A Canadian success story: world-first to treat Fabry disease with gene therapy
newswise.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newswise.com Daily Mail and Mail on Sunday newspapers.

City Of , United Kingdom , Stephen Couban , Darren Bidulka , Aneal Khan , Michael West , Nova Scotians , Deidre Taylor , Armand Keating , Christiane Auray Blais , Ryan Deveau , Anthony Rupar , Amicus Therapeutics , London Health Sciences Centre , University Health Network , Nature Communications , Michener Institute For Education , Alberta Health Services , Takeda Pharmaceuticals , University Of Toronto , Fund Professor , Kidney Foundation Of Canada , Avrobio Inc , Alberta Children Hospital Research Institute , Toronto Rehabilitation Institute , Cumming School Of Medicine ,