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New biomaterials can be 'fine-tuned' for medical applications


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Researchers in the UK and the United States have succeeded in fine tuning a new thermoplastic biomaterial to enable both the rate at which it degrades in the body and its mechanical properties to be controlled independently.
The material, a type of polyester, has been designed for use in soft tissue repair or flexible bioelectronics by a team at the University of Birmingham in the UK and Duke University in the US.
Materials that successfully replicate the necessary elasticity and strength of biological tissues but which also biodegrade over an appropriate timescale are extremely difficult to engineer. This is because the chemistry used to produce a material s mechanical properties will also typically govern the rate at which it degrades. ....

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Post-surgical patch releases non-opioid painkiller directly to the wound


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DURHAM, N.C. - A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away.
The polymer patch provides a controlled release of a drug that blocks the enzyme COX-2 (cyclooxygenase-2,) which drives pain and inflammation. The study appears Jan. 10, 2021 in the
Journal of Controlled Release.
When they started We were making hernia meshes and different antimicrobial films, said Matthew Becker, the Hugo L. Blomquist professor chemistry at Duke, and last author on the paper. We thought you could potentially put pain drugs or anesthetics in the film if you just sew it in as you re stitching the person up, then you wouldn t necessarily have to prescribe any opioids, Becker said. ....

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How your generosity can help save lions in Zambia

Like many of us, Matthew Becker is now used to working from home, kept company by his pet cats and “two spoilt and badly behaved dogs”. His home is rather different, though. He lives in the village of ....

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