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"Dynamic Contrast-Enhanced Ultrasound Radiomics for Hepatocellular Carc" by Qiu Ping Ma, Xue lei He et al.


Abstract
Purpose: To develop a radiomics model based on dynamic contrast-enhanced ultrasound (CEUS) to predict early and late recurrence in patients with a single HCC lesion ≤ 5 cm in diameter after thermal ablation. Procedures: We enrolled patients who underwent thermal ablation for HCC in our hospital from April 2004 to April 2017. Radiomics based on two branch convolution recurrent network was utilized to analyze preoperative dynamic CEUS image of HCC lesions to establish CEUS model, in comparison to the conventional ultrasound (US), clinical, and combined models. Clinical follow-up of HCC recurrence after ablation were taken as reference standard to evaluate the predicted performance of CEUS model and other models. Results: We finally analyzed 318 patients (training cohort: test cohort = 255:63). The combined model showed better performance for early recurrence than CUES (in training cohort, AUC, 0.89 vs. 0.84, P ....

Contrast Enhanced Ultrasound , Hepatocellular Carcinoma , Thermal Ablation , மாறாக மேம்படுத்தப்பட்டது அல்ட்ராசவுண்ட் ,

Blue Earth Diagnostics Announces Dosing of Initial Patient in Phase 3 REVELATE Clinical Trial of 18F-Fluciclovine PET Imaging for Detection of Recurrent Brain Metastases


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- Clinical utility of Axumin (fluciclovine F 18) being investigated in expanded areas of cancer imaging -
Blue Earth Diagnostics, a Bracco company and recognized leader in the development and commercialization of innovative PET radiopharmaceuticals, today announced that the first patient has been dosed in its Phase 3 REVELATE clinical trial of
18F-fluciclovine, a positron emission tomography (PET) imaging radiopharmaceutical being studied for potential use in detecting recurrent brain metastases. The REVELATE study is a Phase 3, multi-center, single-arm imaging study being conducted in the United States. Its purpose is to assess the diagnostic performance of
18F-fluciclovine PET in detecting recurrent brain metastases in patients previously treated with radiation therapy. The first patient dosed in the study was at Yale University, New Haven, Conn., under the auspices of Dr. Mariam Aboian, Assistant Professor of Radiology. ....

United States , United Kingdom , Samuelt Chao , Mariam Aboian , Peter Gardiner , Priscilla Harlan , Jonathan Allis , Kostenloser Wertpapierhandel , Clare Gidley , Mike Beyer , Yale University , Emory University , Drug Administration , Emory University Department Of Radiology , Sam Brown Inc , Bracco Group , Nuclear Medicine , Corporate Communications , European Union , Imaging Sciences , Department Of Radiation Oncology , Ge Healthcare , Earth Diagnostics , New Haven , Assistant Professor , Blue Earth Diagnostics ,