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UNION therapeutics’ COVID-19 candidates show promising results in phase 1 study Apr 7 2021 UNION therapeutics A/S (UNION) announced today that the results of a phase 1 study of inhaled and intranasal niclosamide (UNI911) have been published by The Lancet Regional Health – Europe (LINK). With no serious adverse effects reported, the study showed a strong safety profile of inhaled and intranasal niclosamide which was the primary endpoint for the trial. The promising safety and pharmacokinetic results for inhaled and intranasal niclosamide have opened the doors for further investigation, and will now be tested as a potential treatment (UNI91104) and prophylaxis (UNI91103) for COVID-19. Niclosamide was shown by Institut Pasteur to have a 40-fold better potency than remdesivir against SARS-CoV-2. ....
UNION therapeutics COVID-19 candidates found to be well tolerated in Phase 1 Lancet publication The Lancet Regional Health - Europe has published the results of UNION therapeutics phase 1 study of inhaled and intranasal niclosamide products (UNI91103 and UNI91104) The study endpoints were to assess the safety profile and the pharmacokinetic profile of niclosamide when administered as a nasal spray and as an inhalation product (nebulizer) The study was placebo-controlled and conducted in healthy volunteers No adverse effects were identified, paving the way for further investigation in COVID-19 patients On the basis of these results UNI91103 has been selected as the first intervention of the PROTECT-V study, which recently received UK Urgent Public Heath prioritization ....
The PROTECT-V trial investigating UNIONs COVID-19 candidate receives Urgent Public Health Prioritization from the UK government finanznachrichten.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from finanznachrichten.de Daily Mail and Mail on Sunday newspapers.
Courtesy of Audrey L. Blewer Audrey Blewer had an early interest in history, concentrating on Latin America at the University of Florida in Gainesville. Along the way, though, she took an interest in public health and switched to that discipline for her master’s degree at the school, studying the health of imprisoned women. She went on to earn a Ph.D. in epidemiology at the University of Pennsylvania. She is now an assistant professor of family medicine and community health at Duke University School of Medicine. Her recent studies in cardiopulmonary resuscitation (CPR) incidents, the subject of her dissertation, have shown that women receive it less often than men, leading to the development of a CPR dummy with breasts for professional and civilian training. Her further studies suggest that CPR training dissemination strategies can be expanded and better fitted to address geographic, racial, and socioeconomic disparities in CPR education and delivery, especially at the hands ....
(DTU Biosustain) New research suggests that the diversity of the microbial community involved in sugarcane ethanol fermentation processes plays a significant role in its performance. Selecting the right bacteria could increase ethanol production by more than a billion liters per year, considering Brazil alone. In a study recently published in Nature Communications, scientists from The Novo Nordisk Foundation Center for Biosustainability (DTU) and Yale University have investigated how bacteria that are commonly found in sugarcane ethanol fermentation affect the industrial process. By closely studying the interactions between yeast and bacteria, it is suggested that the industry could improve both its total yield and the cost of the fermentation processes by paying more attention to the diversity of the microbial communities and choosing between good and bad bacteria. ....