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Study quantifies how many children in the U.S. have lost a parent during Covid-19 pandemic


Study quantifies how many children in the U.S. have lost a parent during Covid-19 pandemic
A letter published in
JAMA Pediatrics, co-authored by Rachel Kidman, PhD, of the Program in Public Health at Stony Brook University, presents a statistical model showing that around 40,000 children (est. between 37,000 and 43,000) had lost a parent due to the Covid-19 pandemic by February 2021. This amounts to an average of one child losing a parent for every 13 Covid-19 deaths.
Children face immense challenges in the wake of the pandemic. While there have been anecdotal reports of children losing parents, this is the first study to estimate the increase in orphan rates nationwide. The authors also published an Op Ed in the ....

District Of Columbia , United States , Ashton Verdery , Emily Smith Greenaway , Rachel Kidman , Rachel Margolis , Emily Henderson , Renaissance School Of Medicine , Washington Post , Pennsylvania State University , University Of Western Ontario , University Of Southern California , Program Of Public Health , Public Health , Stony Brook University , Associate Professor , Preventive Medicine , Renaissance School , Western Ontario , Southern California , Pennsylvania State , மாவட்டம் ஆஃப் கொலம்பியா , ஒன்றுபட்டது மாநிலங்களில் , ஆஷ்டன் வெர்டேறி , எமிலி ஸ்மித் கிரீன்வே , ரேச்சல் கிட்மந் ,

40K kids in the US may have lost a parent to COVID-19


Approximately 40,000 children in the United States may have lost a parent to COVID-19 since February 2020, according to a statistical model.
The researchers anticipate that without immediate interventions, the trauma from losing a parent could cast a shadow of mental health and economic problems well into the future for this vulnerable population.
In the researchers’ model, for approximately every 13th COVID-related death, a child loses one parent. Children who lose a parent have a higher risk of a range of problems, including traumatic prolonged grief and depression, lower educational attainment, economic insecurity, and accidental death or suicide, says Ashton Verdery, associate professor of sociology, demography, and social data analytics at Penn State. ....

United States , Ashton Verdery , Rachel Kidman , Centers For Disease , Renaissance School Of Medicine , National Institute On , Penn State Population Research Institute , University Of Western Ontario , Population Research Institute At Penn , University Of Southern California , Institute For Computational , Data Sciences , Disease Control , Population Research Institute , Renaissance School , Public Health , Stony Brook , Social Security , Western Ontario , National Institute , ஒன்றுபட்டது மாநிலங்களில் , ஆஷ்டன் வெர்டேறி , ரேச்சல் கிட்மந் , மையங்கள் க்கு நோய் , மறுமலர்ச்சி பள்ளி ஆஃப் மருந்து , தேசிய நிறுவனம் ஆன் ,

KRAS gene may drive immune 'evasion' in pancreatic cancer


These mutations occur in more than 90% of pancreatic cancer cases and drastically reduce response to immunotherapy.
A new study in
Nature Communications takes an initial step toward better understanding how KRAS drives immune evasion and demonstrates a lowering of the KRAS activity resulting in a more favorable immune environment to fight cancer.
Previous strategies to block the KRAS oncogene therapeutically have focused on counteracting its growth-promoting role in cancer.
“Instead, our study shows that oncogenic KRAS plays a profound immunosuppressive role in cancer maintenance, and that treatment of cancer will be improved by simultaneously inhibiting KRAS and activating immune pathways suppressed by the cancer,” says Oleksi Petrenko, research assistant professor in the department of microbiology and immunology in the Renaissance School of Medicine at Stony Brook University. ....

Nancyc Reich , Oleksi Petrenko , Renaissance School Of Medicine , Nature Communications , National Institutes Of Health Cancer Institute , Catacosinos Cancer Research Award To Petrenko , Stony Brook University Cancer Center , Renaissance School , Stony Brook , Scott Powers , Stony Brook University Cancer , National Institutes , National Cancer Institute , Breast Cancer Research Award , Catacosinos Cancer Research Award , மறுமலர்ச்சி பள்ளி ஆஃப் மருந்து , இயற்கை தகவல்தொடர்புகள் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் புற்றுநோய் நிறுவனம் , ஸ்டோனி சிற்றாறு பல்கலைக்கழகம் புற்றுநோய் மையம் , மறுமலர்ச்சி பள்ளி , ஸ்டோனி சிற்றாறு , ஸ்காட் பவர்ஸ் , ஸ்டோனி சிற்றாறு பல்கலைக்கழகம் புற்றுநோய் , தேசிய நிறுவனங்கள் , தேசிய புற்றுநோய் நிறுவனம் , மார்பக புற்றுநோய் ஆராய்ச்சி விருது ,