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High blood cholesterol might speed up development of dementia vestnikkavkaza.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from vestnikkavkaza.net Daily Mail and Mail on Sunday newspapers.
E-Mail IMAGE: Investigators with the National Institute on Aging, part of the National Institutes of Health, are searching for drug candidates that may correct the brain s metabolic abnormalities, such as cholesterol breakdown. view more Credit: Dr. Vijay R. Varma The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimer s disease and vascular dementia. However, the underlying mechanisms mediating this relationship are poorly understood. A study published in the open-access journal PLOS Medicine by Vijay Varma and colleagues at the National Institute on Aging, part of the National Institutes of Health, in Baltimore, Maryland, suggests that disturbances in the conversion of cholesterol to bile acids (called cholesterol catabolism) may play a role in the development of dementia. ....
atulpmrApril 24, 2021 1 The Drug Repurposing Market report by Persistence Market Research is focusing on the fact that healthcare providers are into collection of socioeconomic information of the patients, so that tracking at any point of time is possible. This on-the-go monitoring is amongst the ongoing trends in the healthcare industry. Drug repurposing or re-profiling has been the hallmark to bring strong business growth and the trend is being followed by majority of the pharmaceutical and biopharmaceutical companies. Among all biologics approved in the U.S. during 2007-2009, 30-40% of them were the drugs repurposed or repositioned. National Institute of Health (NIH), U.S. Department of Health defines drug repurposing as discovering new uses for approved drugs to provide the quickest possible transition from bench to bedside. Drug repurposing opens up various opportunities to answer current unmet medical needs to come up with cost-effective solutions to expensive ....
COVID-19 in Europe – one year on from the first case drugtargetreview.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from drugtargetreview.com Daily Mail and Mail on Sunday newspapers.
Researchers use AI to identify drugs that could be repurposed for Alzheimer’s Eli Lilly s JAK inhibitor Olumiant identified as a potential treatment for repurposing Researchers from Harvard Medical School and Massachussetts General Hospital have revealed which drugs could be potentially repurposed as possible treatments for Alzheimer’s disease using artificial intelligence (AI). The research team developed an AI-based method that enabled them to screen US Food and Drug Administration (FDA) approved medications for their potential as repurposed Alzheimer’s treatments. The study, published in Nature Communications, used a framework called DRIAD (Drug Repurposing in Alzheimer’s Disease) which uses machine learning to measure what happens to human brain neural cells when treated with a drug. ....