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Lifting FDA restrictions on mifepristone could normalize medication abortion

Lifting FDA restrictions on mifepristone could normalize medication abortion
In a new study published online in spring 2021 and in the July issue of the journal
Contraception, University of Chicago Medicine investigators and colleagues interviewed primary care providers in Illinois about their interest in providing medication abortion care and found that lifting FDA restrictions on mifepristone to allow pharmacy dispensing could normalize medication abortion, facilitate its use in primary care facilities, and address disparities in reproductive health access.
Mifepristone is used in combination with misoprostol to end early pregnancies, during the first trimester, said senior author Debra Stulberg, MD, MAPP, Chair of the Department of Family Medicine at the UChicago Medicine. The two-drug regimen is safe and highly effective, but access is limited by a strict Risk Evaluation and Mitigation Strategy (REMS) that prohibits pharmacy dispensing of mifepristone. ....

United States , University Of Chicago , Danielle Calloway , Elizabeth Janiak , Debra Stulberg , Kayla Rasmussen , Emily Henderson , American Academy Of Family Physicians , American College Of Obstetricians , Pritzker School Of Medicine , Department Of Family Medicine , University Of Chicago Medicine , Harvard Medical School , Chicago Medicine , Family Medicine , Risk Evaluation , Mitigation Strategy , Study First Author , Medical Student , Pritzker School , Harvard Medical , American College , American Academy , Family Physicians , Medical School , Primary Care ,

Study finds physicians support pharmacy dispensing to expand access to medication abortion

Interviews with primary care providers showed support for removal of the FDA s mifepristone Risk Evaluation and Mitigation Strategy, which prevents pharmacists from dispensing the drugs needed for medication abortions. ....

University Of Chicago , United States , Hyde Park , Orland Park , Bernard Mitchell Hospital , United Kingdom , Alischera Cottrill , Danielle Calloway , Elizabeth Janiak , Debra Stulberg , Kayla Rasmussen , American Academy Of Family Physicians , Irving Harris Foundation , University Of Chicago Medicine Biological Sciences , Duchossois Center , Department Of Family Medicine , University Of Chicago Medicine , Cancer Center , Sciences Division , Harvard Medical School , University Of Chicago Medical Center , Cambridge Reproductive Health Consultants , American College Of Obstetricians , Pritzker School Of Medicine , Parenthood League , Chicago Medicine ,

Greater presence of family docs, midwives may decrease rates of cesarean birth

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Surgical cesarean births can expose new mothers to a range of health complications, including infection, blood clots and hemorrhage. As part of Healthy People 2020 and other maternal health objectives, the state of California exerted pressure to reduce cesarean deliveries, and statewide organizations established quality initiatives in partnership with those goals. In this study, researchers from Stanford University and the University of Chicago examined unit culture and provider mix differences on hospital and delivery units to identify characteristics of units that successfully reduced their cesarean delivery rates. The mixed-methods study surveyed and interviewed labor and delivery teams from 37 California hospitals that were participating sites in the California Maternal Quality Care Collaborative s Supporting Vaginal Birth initiative. Respondents at successful hospitals included more family physicians and midwives, and physicians who had been in practice for less ....

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Successful DNA replication in cyanobacteria depends on the circadian clock

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IMAGE: DNA replication cycles are tied to the circadian clock, and interruptions can lead to incomplete chromosomes.
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Credit: Image courtesy of Yi Liao.
A new study from the University of Chicago has found that the photosynthetic bacterium Synechococcus elongatus uses a circadian clock to precisely time DNA replication, and that interrupting this circadian rhythm prevents replication from completing and leaves chromosomes unfinished overnight. The results, published online on May 10 in
Circadian rhythms are the internal 24-hour clock possessed by most organisms on earth, regulating a diversity of biological functions including sleep/wake cycles, hormone production, digestion and body temperature. In humans, disruptions to the circadian rhythm such as working a shift-work job or experiencing frequent jet lag have been associated with an array of health problems, including obesity, cardiovascular and immune dysfunction, mood disor ....

Yi Liao , Cancer Center , Sciences Division , University Of Chicago Medical Center , University Of Chicago Medicine Biological Sciences , Duchossois Center , Pritzker School Of Medicine , University Of Chicago , University Of Chicago Medicine , Howard Hughes Medical Institute Simons Faculty Scholar , National Academy , Michael Rust , Associate Professor , Molecular Genetics , Cell Biology , Industrial Revolution , Howard Hughes Medical Institute , Simons Faculty Scholar , Chicago Medicine , Biological Sciences , Chicago Medical Center , Pritzker School , Twelve Nobel Prize , Hyde Park , Bernard Mitchell Hospital , Comer Children ,

May/June 2021 Annals of Family Medicine tip sheet

Greater Presence of Family Physicians, Midwives May Be Key Component to Decreasing Cesarean Delivery Rates
Surgical cesarean births can expose new mothers to a range of health complications, including infection, blood clots and hemorrhage. As part of Healthy People 2020 and other maternal health objectives, the state of California exerted pressure to reduce cesarean deliveries, and statewide organizations established quality initiatives in partnership with those goals. In this study, researchers from Stanford University and the University of Chicago examined unit culture and provider mix differences on hospital and delivery units to identify characteristics of units that successfully reduced their cesarean delivery rates. The mixed-methods study surveyed and interviewed labor and delivery teams from 37 California hospitals that were participating sites in the California Maternal Quality Care Collaborative s Supporting Vaginal Birth initiative. Respondents at successful hospita ....

New York , United States , New Zealand , University Of Chicago , North Carolina , Stanford University , Albany Medical College , Noord Holland , Tufts University , University Of North Carolina , University School , Takashi Chinen , Janelle Davis , Melissab Hill , Elena Rosenbaum , Emilyc White Vangompel , Robertl Phillips , Randi Sokol , Anna Perera , Pim Cuijpers , Aphrodite Papadakis , Robertl Phillips Jr , Vrije Universiteit , Amy Russell , Martijnjl Verhulst , Deborahj Cohen ,