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Seagen Inc.: Seagen Announces Long-Term Results from TUKYSA (tucatinib) Pivotal Trial in Patients with HER2-Positive Breast Cancer During the Virtual Scientific Program of the 2021 ASCO Annual Meeting


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- Updated Analysis Shows Median Overall Survival for TUKYSA Arm Extended to Two Years, with Benefit Maintained Across All Prespecified Patient Subgroups in HER2CLIMB Trial -
- Results Further Support TUKYSA as Well-Tolerated Treatment Option That Improves Survival in Patients with Previously Treated Metastatic HER2-Positive Breast Cancer With and Without Brain Metastases -
Seagen Inc. (Nasdaq:SGEN) today announced that improvements in overall survival (OS) and progression-free survival (PFS) were maintained with long-term follow up from the pivotal HER2CLIMB trial evaluating the addition of TUKYSA
(tucatinib) to trastuzumab and capecitabine in patients with HER2-positive metastatic breast cancer (MBC) with and without brain metastases. Data from the pre-specified exploratory analysis will be presented (Abstract #1043) as part of the virtual scientific program of the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting. ....

United States , David Caouette , Rogerd Dansey , Giuseppe Curigliano , Peggy Pinkston , American Society Of Clinical Oncology , World Health Organization , Drug Administration , University Of Milano , Lab Abnormalities , Regulatory Agency , Seagen Inc , Exchange Commission , Corporate Communications , European Union , European Medicines Agency , European Institute Of Oncology , American Cancer Society , Analysis Shows Median Overall Survival , Two Years , Further Support , Previously Treated Metastatic , Positive Breast Cancer With , Without Brain Metastases , Clinical Oncology , Early Drug Development ,