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Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Critical mechanism allows deadly bacteria to gain resistance to antibiotics
Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics.
The findings offer a potential new drug target in the search for effective new antibiotics as we face the growing threat of antimicrobial resistance (AMR) and infections caused by bacterial pathogens.
The study investigated quinolone antibiotics which are used to treat a range of bacterial infections, including TB (tuberculosis). Quinolones work by inhibiting bacterial enzymes, gyrase and topoisomerase IV, thereby preventing DNA replication and RNA synthesis essential to growth.
They are highly-successful antimicrobial agents widely used in current medicine, however bacterial resistance to them and other treatments is a serious problem. ....

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Russian opposition leader Navalny isolated with transfer "to remove him from Moscow," lawyer says

Imprisoned in the capital, Alexey Navalny continued to challenge Vladimir Putin's authority. Now he's miles away, and knows "even less about what is happening in the outside world." ....

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Tough US Sanctions On Russia Over Poisoning And Jailing Aleksey Navalny

Tough US Sanctions On Russia Over Poisoning And Jailing Aleksey Navalny
MOSCOW (dpa-AFX) - The United States has imposed a tough set of sanctions on Russia over the attempted assassination and subsequent imprisonment of Russian opposition leader Aleksey Navalny.
Announcing the sanctions at a press briefing, White House Press Secretary Jen Psaki said the U.S. intelligence community assesses with high confidence that officers of Russia s Federal Security Service used a nerve agent to poison Navalny on August 20.
Psaki said the measures were taken also to hold Russia accountable for jailing the opposition leader in January 2021.
The State Department expanded existing sanctions under the Chemical and Biological Weapons Control and Warfare Elimination Act. ....

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US slaps sanctions against Russian officials over Navalny's poisoning, imprisonment

Washington [US], March 2 (ANI): US President Joe Biden's administration has slapped sanctions on seven Russian officials in response to the poisoning and imprisonment of Kremlin critic Alexey Navalny. ....

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