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Lab study of South African SARS-CoV-2 variant and Moderna vaccine: reduced neutralization, but still protective

Researchers from the US recently compared antibody binding and viral neutralization against 2 SARS-CoV-2 variants that emerged in different parts of the world. The researchers used sera from spike mRNA vaccinated and naturally infected individuals against a circulating B.1 variant and the emerging B.1.351 variant. The study is published on the preprint server bioRxiv. ....

South Africa , Eastern Cape , South African , Susha Cheriyedath , Coronavirus Disease Covid 19 , Sars Cov 2 , Angiotensin Converting Enzyme 2 , Aspartic Acid , Corona Virus , Immune System , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , கிழக்கு கேப் , கொரோனா வைரஸ் , நோய் எதிர்ப்பு சக்தி அமைப்பு , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

Less salt content in Parmigiano Reggiano cheese may not affect its distinctive flavor

Less salt content in Parmigiano Reggiano cheese may not affect its distinctive flavor
Aged cheeses pack a punch of nutty, sharp flavor. Before they re fully mature, aged cheeses are either waxed or placed in brine for weeks to create a natural rind. However, the high salt content in brined cheeses deters some consumers.
Now, researchers reporting in
ACS Food Science & Technology present a shortened brining time for Parmigiano Reggiano that results in a less salty product, while still potentially maintaining the cheese s distinctive texture and flavor compounds.
Parmigiano Reggiano is a lactose-free, crumbly and hard cheese. Manufactured in select provinces in Italy, its protected designation of origin status requires that certain production processes, such as a minimum 12-month ripening period, be performed. ....

Silvia Marzocchi , Parmigiano Reggiano , Emily Henderson , Food Science Technology , Fatty Acids , சில்வியா மார்சோச்சி , பர்மிகியானோ ரெஜியானோ , எமிலி ஹென்டர்சன் , உணவு அறிவியல் தொழில்நுட்பம் , கொழுப்பு அமிலங்கள் ,

High expression of ACE2 receptors in developing ovaries increases SARS-CoV-2 risk

A team of scientists from China collaborated to find if SARS-CoV-2 could also infect the ovary at different developmental stages. ....

Jocelyn Solis Moreirafeb , Jocelyn Solis Moreira , Gene Ontology , Sars Cov 2 , Angiotensin Converting Enzyme 2 , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Somatic Cells , ஜாஸ்லைந் ஸோலிஸ் மோர்ர , கீந் இயக்கவியல் , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , சோமாடிக் செல்கள் ,

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children
A study aiming to develop a new therapeutic technique could bring a revolution in our approach to treating rare, fatal Sanfilippo syndrome, a disorder that affects children as young as 2 years old and leads to childhood dementia and premature death.
We are using a combination of gene therapy, stem cells and small molecules to restore metabolic defects in the patient s brain cells. First results in the mouse models of the disease are very encouraging.
Dr. Alexey Pshezhetsky, Professor at CHU Ste-Justine and Lead GlycoNet Investigator
Sanfilippo syndrome belongs to a group of rare diseases known as lysosomal storage disorders. ....

Alexey Pshezhetsky , Emily Henderson , Glyconet Investigator , Ashkenazi Jewish , French Canadians , Gene Therapy , Lysosomal Storage Disorders , Sanfilippo Syndrome , Stem Cells , எமிலி ஹென்டர்சன் , பிரஞ்சு கனடியர்கள் , கீந் சிகிச்சை , சான்ஃபிலிப்போ நோய்க்குறி , தண்டு செல்கள் ,

Researchers discover new functions of the ENDOU enzyme

Researchers discover new functions of the ENDOU enzyme
Researchers at Freiburg University discover new functions of the widely disseminated, yet little understood ENDOU enzyme.
The family of ENDOU enzymes is found in most organisms, yet its functions are only poorly understood. In humans, it has been connected with cancer.
RNA viruses, such as SARS-CoV2, contain a gene corresponding to ENDOU, and this is important for virus replication and the suppression of the immune response. However, so far only a few details of the role of these enzymes are known.
The research group led by the molecular geneticist Dr. Wenjing Qi from the University of Freiburg now contributes some more details to its function in a study published by the renowned scientific journal Nature Communications . They suggest that the gene ENDU-2 could be responsible for triggering tumors in the body from a distance. ....

Wenjing Qi , Ralf Baumeister , Emily Henderson , Centre For Biological Signalling , Nature Communications , German Research Foundation , University Of Freiburg , Researchers At Freiburg University , Centre For Integrative Biological Signalling , Freiburg University , Molecular Geneticist , Biological Signalling Studies , Excellence Cluster , Integrative Biological Signalling Studies , Immune Response , எமிலி ஹென்டர்சன் , இயற்கை தகவல்தொடர்புகள் , ஜெர்மன் ஆராய்ச்சி அடித்தளம் , மூலக்கூறு ஜெநெடிஸிஸ்ட் , சிறப்பானது கொத்து , நோய் எதிர்ப்பு சக்தி பதில் , மன அழுத்தம் ,