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Experiment Uses CRISPR To Edit Genes While They Are Still Inside A Person's Body : Shots


Josh Andersen/Oregon Health & Science University
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Josh Andersen/Oregon Health & Science University
Carlene Knight, 54, is one of the first patients in a landmark study designed to try to restore vision in those who have a rare genetic disease that causes blindness.
Josh Andersen/Oregon Health & Science University
Carlene Knight would love to do things that most people take for granted, such as read books, drive a car, ride a bike, gaze at animals in a zoo and watch movies. She also longs to see expressions on people s faces.
To be able to see my granddaughter especially my granddaughter s face, said Knight, 54, who lives outside Portland, Ore. It would be huge. ....

New York , United States , Long Island , Mark Pennesi , Michael Kalberer , Josh Andersen , Elisa Michaels , Carlene Knight , Oregon Health Science University In Portland , Editas Medicine , Eric Pierce , Mass Eye , Mass General Brigham , Jason Comander , Oregon Health , Science University , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , நீண்டது தீவு , ஜோஷ் ஆண்டர்சன் , லிசா மைக்கேல்ஸ் , ஓரிகந் ஆரோக்கியம் அறிவியல் பல்கலைக்கழகம் இல் போர்டிலந்ட் , எரிக் துளை , நிறை கண் , நிறை ஜநரல் ப்ரிகாம் , ஓரிகந் ஆரோக்கியம் ,

Blind Patients Hope Landmark Gene-Editing Experiment Will Restore Their Vision


Listen • 5:27
Carlene Knight, 54, is one of the first patients in a landmark study designed to try to restore vision in those who have a rare genetic disease that causes blindness.
Carlene Knight would love to do things that most people take for granted, such as read books, drive a car, ride a bike, gaze at animals in a zoo and watch movies. She also longs to see expressions on people s faces.
To be able to see my granddaughter especially my granddaughter s face, said Knight, 54, who lives outside Portland, Ore. It would be huge.
Michael Kalberer yearns to be able to read a computer screen so he could get back to work as a social worker. He also hopes to one day watch his nieces and nephews play soccer instead of just listening to them, and move around in the world without help. But that s not all. ....

New York , United States , Long Island , Mark Pennesi , Michael Kalberer , Elisa Michaels , Carlene Knight , Oregon Health Science University In Portland , Editas Medicine , Eric Pierce , Mass Eye , Mass General Brigham , Jason Comander , Oregon Health , Science University , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , நீண்டது தீவு , லிசா மைக்கேல்ஸ் , ஓரிகந் ஆரோக்கியம் அறிவியல் பல்கலைக்கழகம் இல் போர்டிலந்ட் , எரிக் துளை , நிறை கண் , நிறை ஜநரல் ப்ரிகாம் , ஓரிகந் ஆரோக்கியம் , அறிவியல் பல்கலைக்கழகம் ,

Blind patients hope to gain vision in medical first of CRISPR editing DNA inside their bodies


Gene-editing CRISPR tool is used INSIDE four blind patients bodies in a world-first attempt to correct their vision without transferring DNA to the lab
Carlene Knight and Michael Kalberer were both born with a rare genetic eye disorder called Leber congenital amaurosis (LCA)
Patients with LCA have genetic mutations that cause rods and cones, cells that detect light in the retina, to not function properly and that lead to vision loss
Knight, 54, from Portland, Oregon, and Kalberer, 43, from Long Island, New York, have volunteered for a gene-editing study using CRISPR technology 
Traditionally, cells with mutations are removed from the body, the defective genes are edited out, and then the cells are inserted back in ....

New York , United States , United Kingdom , Long Island , Michael Kalberer , Elisa Michaels , Carlene Knight , National Organization For Rare Disorders , Editas Medicine , National Organization , Mass Eye , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , நீண்டது தீவு , லிசா மைக்கேல்ஸ் , தேசிய ஆர்கநைஸேஶந் க்கு ரேர் கோளாறுகள் , தேசிய ஆர்கநைஸேஶந் , நிறை கண் ,

Sleep disorders increase health care utilization and costs


Sleep disorders increase health care utilization and costs
Sleep disorders are associated with significantly higher rates of health care utilization, conservatively placing an additional $94.9 billion in costs each year to the United States health care system, according to a new study from researchers at Mass Eye and Ear, a member hospital of Mass General Brigham.
In their new analysis, published in the
Journal of Clinical Sleep Medicine, the researchers found the number of medical visits and prescriptions filled were nearly doubled in people with sleep disorders such as sleep apnea and insomnia, compared to similar people without. Affected patients were also more likely to visit the emergency department and have more comorbid medical conditions. ....

United States , Emily Henderson , Human Service Agency For Healthcare Research , Department Of Health , Expenditure Panel , Mass Eye , Mass General , Clinical Sleep Medicine , Expenditure Panel Survey , Human Service Agency , Healthcare Research , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , துறை ஆஃப் ஆரோக்கியம் , செலவு குழு , நிறை கண் , நிறை ஜநரல் , மருத்துவ தூங்கு மருந்து , செலவு குழு கணக்கெடுப்பு , சுகாதாரம் ஆராய்ச்சி ,