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Green chemistry and biofuel: the mechanism of a key photoenzyme decrypted

Green chemistry and biofuel: the mechanism of a key photoenzyme decrypted
08-04-2021
The functioning of the enzyme FAP, useful for producing biofuels and for green chemistry, has been decrypted. This result mobilized an international team of scientists, including many French researchers from the CEA, CNRS, Inserm, École Polytechnique, the universities of Grenoble Alpes, Paris-Saclay and Aix Marseille, as well as the European Synchrotron (ESRF) and synchrotron SOLEIL. The study is published in Science on April 09, 2021.
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The researchers decrypted the operating mechanisms of FAP (Fatty Acid Photodecarboxylase), which is naturally present in microscopic algae such as Chlorella. The enzyme had been identified in 2017 as able to use light energy to form hydrocarbons from fatty acids produced by these microalgae. To achieve this new result, research teams used a complete experimental and theoretical toolkit. ....

France General , United States , Antoine Royant , Stef Cand , University Of Lille , Max Planck Institute In Heidelberg Germany , Institute Of Structural Biology , Grenoble Alpes University , Laboratory For Optics , French National Research Agency , Spectroscopy Laboratory For Interactions , Saclay University , Biotechnologies Institute Of Aix , Marseille University , Moscow State University Russia , Institute For Integrative Biology Of The Cell , Os Lab , Laue Langevin Institute , National Accelerator Laboratory United States , Fatty Acid Photodecarboxylase , Biotechnologies Institute , Aix Marseille University , Structural Biology , Advanced Spectroscopy Laboratory , Integrative Biology , Paris Saclay University ,

Singapore reveals new study on autoimmune disorders and severe COVID-19

NTU Singapore scientists design a compound called ASO-1 to control a hyperactive immune response ....

Nanyang Technological University , Institute Of Structural Biology , University Of Edinburgh , Professor Phan , Country Code Phone Number , Anti Autoimmune Immune Response , Aso 1 , நிறுவனம் ஆஃப் கட்டமைப்பு உயிரியல் , பல்கலைக்கழகம் ஆஃப் எடின்பர்க் , ப்ரொஃபெஸர் ஃப்யாந் , நாடு குறியீடு தொலைபேசி எண் , எதிர்ப்பு ஆட்டோ இம்யூன் நோய் எதிர்ப்பு சக்தி பதில் ,

NTU scientists design new compound that could help reduce overactive immune response

NTU scientists design new compound that could help reduce overactive immune response
When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune system overreacts, resulting in an overactive immune response that causes the body to injure itself, which may prove fatal in some cases.
Now, scientists from Nanyang Technological University, Singapore (NTU Singapore) have created a compound that could help to reduce this overactivation without impairing the body s entire immune response.
An overactive immune system leads to many autoimmune disorders - when the immune system mistakenly attacks healthy tissues - such as rheumatoid arthritis and type 1 diabetes. More recently, it has also been linked to severe COVID-19 infections, in which immune-system signalling proteins ramp up to dangerous levels, leading to damage to the body s own cells. ....

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NTU Singapore scientists design compound that targets enzyme linked to autoimmune disorders and severe COVID-19

When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune. ....

United States , Phan Anh Tuan , American Association Of Immunologists , Nanyang Technological University , Mathematical Sciences , Institute Of Structural Biology , University Of Edinburgh , Professor Phan Anh Tuan , Structural Biology , Lim Kah Wai , United Kingdom Led , American Association , Senior Research Fellow , Rheumatoid Arthritis , Type 1 Diabetes , Research Fellow , Immune Response , Clinical Trials , Critically Ill , ஒன்றுபட்டது மாநிலங்களில் , ஃப்யாந் அந்த் ட்யூவாந் , அமெரிக்கன் சங்கம் ஆஃப் நோயெதிர்ப்பு நிபுணர்கள் , கணித அறிவியல் , நிறுவனம் ஆஃப் கட்டமைப்பு உயிரியல் , பல்கலைக்கழகம் ஆஃப் எடின்பர்க் , ப்ரொஃபெஸர் ஃப்யாந் அந்த் ட்யூவாந் ,

New compound can reduce overactivation without impairing the body's immunity response

New compound can reduce overactivation without impairing the body s immunity response
When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune system overreacts, resulting in an overactive immune response that causes the body to injure itself, which may prove fatal in some cases.
Now, scientists from Nanyang Technological University, Singapore (NTU Singapore) have created a compound that could help to reduce this overactivation without impairing the body s entire immune response.
An overactive immune system leads to many autoimmune disorders - when the immune system mistakenly attacks healthy tissues - such as rheumatoid arthritis and type 1 diabetes. More recently, it has also been linked to severe COVID-19 infections, in which immune-system signalling proteins ramp up to dangerous levels, leading to damage to the body s own cells. ....

United States , Phan Anh Tuan , Phan Anh , Emily Henderson , American Association Of Immunologists , Nanyang Technological University , Mathematical Sciences , Institute Of Structural Biology , University Of Edinburgh , Professor Phan Anh Tuan , Interim Director , Structural Biology , Nanyang Technological , Lim Kah Wai , United Kingdom Led , American Association , Immune Response , Immune System , Rheumatoid Arthritis , Type 1 Diabetes , ஒன்றுபட்டது மாநிலங்களில் , ஃப்யாந் அந்த் ட்யூவாந் , ஃப்யாந் அந்த் , எமிலி ஹென்டர்சன் , அமெரிக்கன் சங்கம் ஆஃப் நோயெதிர்ப்பு நிபுணர்கள் , கணித அறிவியல் ,