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NTU scientists design new compound that could help reduce overactive immune response


NTU scientists design new compound that could help reduce overactive immune response
When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune system overreacts, resulting in an overactive immune response that causes the body to injure itself, which may prove fatal in some cases.
Now, scientists from Nanyang Technological University, Singapore (NTU Singapore) have created a compound that could help to reduce this overactivation without impairing the body s entire immune response.
An overactive immune system leads to many autoimmune disorders - when the immune system mistakenly attacks healthy tissues - such as rheumatoid arthritis and type 1 diabetes. More recently, it has also been linked to severe COVID-19 infections, in which immune-system signalling proteins ramp up to dangerous levels, leading to damage to the body s own cells. ....

United States , Phan Anh Tuan , Emily Henderson , American Association Of Immunologists , Nanyang Technological University , Mathematical Sciences , Institute Of Structural Biology , University Of Edinburgh , Professor Phan Anh Tuan , Structural Biology , Lim Kah Wai , United Kingdom Led , American Association , Immune Response , Immune System , Rheumatoid Arthritis , Type 1 Diabetes , ஒன்றுபட்டது மாநிலங்களில் , ஃப்யாந் அந்த் ட்யூவாந் , எமிலி ஹென்டர்சன் , அமெரிக்கன் சங்கம் ஆஃப் நோயெதிர்ப்பு நிபுணர்கள் , கணித அறிவியல் , நிறுவனம் ஆஃப் கட்டமைப்பு உயிரியல் , பல்கலைக்கழகம் ஆஃப் எடின்பர்க் , ப்ரொஃபெஸர் ஃப்யாந் அந்த் ட்யூவாந் , கட்டமைப்பு உயிரியல் ,

New compound can reduce overactivation without impairing the body's immunity response


New compound can reduce overactivation without impairing the body s immunity response
When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune system overreacts, resulting in an overactive immune response that causes the body to injure itself, which may prove fatal in some cases.
Now, scientists from Nanyang Technological University, Singapore (NTU Singapore) have created a compound that could help to reduce this overactivation without impairing the body s entire immune response.
An overactive immune system leads to many autoimmune disorders - when the immune system mistakenly attacks healthy tissues - such as rheumatoid arthritis and type 1 diabetes. More recently, it has also been linked to severe COVID-19 infections, in which immune-system signalling proteins ramp up to dangerous levels, leading to damage to the body s own cells. ....

United States , Phan Anh Tuan , Phan Anh , Emily Henderson , American Association Of Immunologists , Nanyang Technological University , Mathematical Sciences , Institute Of Structural Biology , University Of Edinburgh , Professor Phan Anh Tuan , Interim Director , Structural Biology , Nanyang Technological , Lim Kah Wai , United Kingdom Led , American Association , Immune Response , Immune System , Rheumatoid Arthritis , Type 1 Diabetes , ஒன்றுபட்டது மாநிலங்களில் , ஃப்யாந் அந்த் ட்யூவாந் , ஃப்யாந் அந்த் , எமிலி ஹென்டர்சன் , அமெரிக்கன் சங்கம் ஆஃப் நோயெதிர்ப்பு நிபுணர்கள் , கணித அறிவியல் ,