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Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients
Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress syndrome (ARDS) in COVID-19 patients were awarded $5.1 million in funding from the U.S. Department of Defense (DOD) to expand the Phase II clinical trial at The University of Texas Health Science Center at HoustonQ (UTHealth).
Vadadustat is an investigational oral hypoxia-inducible factor prolyl hydroxylase inhibitor, or HIF-PHI, designed to mimic the physiologic effect of altitude on oxygen availability. At higher altitudes, the body responds to lower oxygen availability with stabilization of HIF, which can lead to improved oxygen delivery to tissues. Stabilization of HIF can help to dampen alveolar inflammation, a key problem that patients with COVID-19-associated lung disease are facing when they develop ARDS. The drug is investigational in the U.S. but ....

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Texas hospitals see surge in COVID-19 hospitalizations in wake of the holidays

Adult COVID-19 patients currently in hospital: 60
Percent of adult inpatient beds occupied by COVID-19 patients: 14%
Available adult inpatient beds: 8
Adult COVID-19 patients currently in ICU: 31
Percent of adult ICU beds occupied by COVID-19 patients: 33%
Available adult ICU beds: 1
Texas Childrens Hospital
Percent of adult inpatient beds occupied by COVID-19 patients: 38%
Available adult inpatient beds: 82
Adult COVID-19 patients currently in ICU: 16
Percent of adult ICU beds occupied by COVID-19 patients: N/A
Available adult ICU beds: 0
University of Texas MD Anderson Cancer Center
Adult COVID-19 patients currently in hospital: 79
Percent of adult inpatient beds occupied by COVID-19 patients: 11%
Available adult inpatient beds: 234 ....

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'But what about us?' Some workers on the frontlines of COVID-19 left out of the first round of vaccines.

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Frontline workers at some Houston hospitals in poor areas left out of the first round of vaccines
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1of14Tanna Ingraham, right, is hugged by medical student Pauleth Tenorio, left, inside her room at United Memorial Medical Center, on Friday, Dec. 11, 2020, in Houston. Ingraham, who is a registered nurse and works at UMMC s COVID Unit, has contracted the virus for the second time in six months. As thousands of health care workers at Houston s largest hospitals will be first in line to receive the new COVID-19 vaccine in the coming days, those at smaller institutions, including UMMC will get none.Godofredo A. Vásquez/Staff photographerShow MoreShow Less ....

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These Houston-area hospitals will be first to receive the COVID-19 vaccine

These Houston-area hospitals will be first to receive the COVID-19 vaccine
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Moderna trial participant awaits the shot of new COVID-19 vaccine in Houston s Baylor study.Marie D. De Jesús, Houston Chronicle / Staff photographer
After nine months of waiting, Houston-area hospitals are preparing for their first shipment of Pfizer s COVID-19 vaccine.
The first round of Pfizer s COVID-19 vaccine are now slated to go out on Dec. 14, according to the Texas Department of Health Services. Across the Lone Star State, there will be 224,250 doses shipped to 109 Texas hospitals in 34 counties, according to DSHS.
We could get a supply of vaccine for administration within a day or two of FDA s emergency use approval. We could possibly have a supply as early as next Monday, Memorial Hermann Health System s CEO Dr. David Callender told Chron. Callender added that Houston s Memorial Hermann Health System was promised 16,575 doses of the vaccine by the sta ....

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