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Frontiers | Chronic Obstructive Pulmonary Disease Patients Have Increased Levels of Plasma Inflammatory Mediators Reported Upregulated in Severe COVID-19


2Informatic Unit, INMEDIT SAS and Faculty of Engineering, University of Cartagena, Cartagena, Colombia
3Clinica Respiratoria y de Alergias, Cartagena, Colombia
4Departamento de Investigaciones, Fundación Cardioinfantil, Bogotá, Colombia
5Research Department - CINEUMO, Fundación Neumológica Colombiana, Bogotá, Colombia
6Research Department and Specialization Program in Pulmonology, Universidad de la Sabana, Bogotá, Colombia
Background: Chronic obstructive pulmonary disease (COPD) is associated with increased risk of severe COVID-19, but the mechanisms are unclear. Besides, patients with severe COVID-19 have been reported to have increased levels of several immune mediators.
Methods: Ninety-two proteins were quantified in 315 plasma samples from 118 asthmatics, 99 COPD patients and 98 healthy controls (age 40-90 years), who were recruited in Colombia before the COVID-19 pandemic. Protein levels were compared between each disease group and healthy contro ....

Saint George , Comunidad Autonoma De Cataluna , United States , Uppsala Lan , South Korea , Castillay Leóp , Republic Of Colombia , Dina Ortiz , Tania Cepeda , Saheb Sharif Askari , Kruskal Wallis , Geneshot Gene , Patricia Parada , Al Heialy , Ivan Acevedo Monterrosa , Mileidis Avila , Thromb Haemost , Analysis Service Facility , Airways Expression , Gene Set Library , Airway Immunity Dysfunction , Thermo Fisher , University Of Cartagena , Ministry Of Science Republic Colombia , Inflammation Panel Olink Proteomics , Cells In Health ,

Integration analysis of m6A regulators and m6A-related genes in hepatocellular carcinoma


Announcing a new article publication for
BIO Integration journal. In this article the authors Jingdun Xie, Zhenhua Qi, Xiaolin Luo, Fang Yan, Wei Xing, Weian Zeng, Dongtai Chen and Qiang Li; from Sun Yat-sen University, Guangzhou, Guangdong, China discuss integration analysis of m6A regulators and m6A-related genes in hepatocellular carcinoma (HCC).
N6-Methyladenosine (m6A) RNA methylation of eukaryotic mRNA is involved in the progression of various tumors. This study comprehensively analyzed m6A regulators and m6A-related genes through an integrated bioinformatic analysis, including expression, clustering, protein-protein interaction, and prognosis, thus providing novel insights into the roles of m6A regulators and m6A-related genes in HCC. ....

Qiang Li , Wei Xing , Dongtai Chen , Fang Yan , Zhenhua Qi , Xiaolin Luo , Jingdun Xie , Weian Zeng , Sun Yat Sen University , Integration Analysis , Related Genes , Medicine Health , கியாங் லி , வெய் க்ஷிங் , ஃப்யாஂக் யான் , சூரியன் யத் சென் பல்கலைக்கழகம் , ஒருங்கிணைப்பு பகுப்பாய்வு , தொடர்புடையது ஜீந்ஸ் , மருந்து ஆரோக்கியம் ,