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Report sounds alarm on efficacy, safety, ethics of embryo selection with polygenic scores


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Special report conducted by multinational team of researchers from University of Southern California, Geisinger Health System, UCLA, National Bureau of Economic Research, New York University, Harvard University, Broad Institute of Harvard and MIT, Harvard Medical School, Massachusetts General Hospital, Brigham and Women s Hospital, University of Queensland
July 1, 2021 A special report published today in the
New England Journal of Medicine raises serious questions about the benefits, risks and ethics of a new service which the authors call embryo selection based on polygenic scores, or ESPS that allows in vitro fertilization patients to select embryos with the goal of choosing healthier and even smarter children. ....

Anderson School , United States , Harvard University , Nancy Wang , Michelle Meyer , Peterm Visscher , David Laibson , David Sampson , Heidil Rehm , Ashley Andyshak Hayes , Danielj Benjamin , Patrick Turley , David Cesarini , Jenesse Miller , Louise Wilkins Haug , Evelynn Hammonds , Aliciar Martin , Michellen Meyer , Steven Hyman , Benm Neale , National Health , University Of Queensland , University Of Southern California , Stanley Family Foundation , Robert Wood Johnson Foundation , Geisinger Health System ,

binx health requests EUA for CRISPR-based test for COVID-19


Industry News: binx health submits request for Emergency Use Authorization for first CRISPR-based point-of-care test for COVID-19
Platform poised to be first CLIA-waived CRISPR-based, point-of-care COVID-19 device with central-lab performance, developed in collaboration with Sherlock Biosciences
18 May 2021
binx health has announced the submission of an Emergency Use Authorization (EUA) request to the U.S. Food and Drug Administration (FDA) for the first CLIA-waived CRISPR-based point-of-care (POC) test for COVID-19. binx io is already the first CLIA-waived platform for the molecular detection of chlamydia and gonorrhea in about 30 minutes. binx has now adapted the single-use cartridge for analysis of RNA-based targets, pairing the high performance of Sherlock Biosciences’ proprietary CRISPR technology with binx’s rapid and sensitive proprietary electrochemical detection to create a powerful tool to help combat COVID-19. Data obtained in support of this authorizati ....

Jeffrey Luber , Sherlock Biosciences , Rahul Dhanda , Sherlock Bioscience , Clinical Laboratory Improvement Amendments , Drug Administration , Industry News , Emergency Use Authorization , Chief Executive , Open Philanthropy , Chief Executive Officer , Synthetic Biology , Specific High Sensitivity Enzymatic Reporter , Binx Health Submits Request For Emergency Use Authorization First Crispr Based Point Of Care Test Covid 19 Diagnostic , ஜெஃப்ரி லூபர் , ஷெர்லாக் உயிர் அறிவியல் , ராகுல் தண்டா , ஷெர்லாக் உயிர் அறிவியல் , மருத்துவ ஆய்வகம் முன்னேற்றம் திருத்தங்கள் , தொழில் செய்தி , அவசரம் பயன்பாடு அங்கீகாரம் , தலைமை நிர்வாகி , திறந்த பரோபகாரம் , தலைமை நிர்வாகி அதிகாரி , செயற்கை உயிரியல் , குறிப்பிட்ட உயர் உணர்திறன் நொதி நிருபர் ,

Toward practical stratospheric aerosol albedo modification: Solar-powered lofting


The burden is summed from 200 hPa to the model top at 10 hPa. (
A) Burden remaining from a 2 Tg year
−1 of SO
2 injection at 20 km (dotted line), at 13.5 km (dashed line), and at 13.5 km including BC (solid line). For each scenario, the injection was over a 10-day period every June at the equator. (
B) Burden for the injection at 13.5 km including BC in latitude bands: Solid line is global, dashed line is 30°N to 30°S, dotted line is 30°N to 90°N, and dash-dotted line is 30°S to 90°S. The model is running in a free mode, so there is natural variability in the dynamics impacting the aerosol loading from year to year. It takes approximately 2 years to reach a pseudo equilibrium loading, and interannual variability is apparent in the last 4 years plotted. ....

United States , France General , Bureau Of Transportation Statistics , Climate Simulation Laboratory , National Center , Information Systems Laboratory , Community Aerosol , National Science Foundation Department Of Energy , Atmospheric Research , National Oceanic , Atmospheric Administration , University Of Nevada , Aerosol Robotic Network , Research Program , Un Framework Convention On Climate Change , Community Earth System Model , Paris Agreement , Climate Change , Pacific Northwest , Northern Hemisphere , Radiation Model , Representative Concentration Pathway , Southern Hemispheres , Transportation Statistics , National Science , Rapid Radiative Transfer Model ,