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Virulent Newcastle Disease Viruses Circulating in Ethiopia


↓ cleavage residues indicate that the NDV isolates correspond to mesogenic/velogenic pathotypes.
Figure 2 Deduced amino acid sequence alignment of F gene sequences of NDV strains isolated from Ethiopia. Names of strains are shown on the left-hand side of the figure. Identification with the reference La Sota (genotype II) vaccine strains is indicated by dots. They indicate the cleavage site of the deduced aa sequence of the F gene. X indicates an ambiguous aa sequence.
Abbreviations: Eth, Ethiopia; Chk, chicken.
Genetic Distance
The Ethiopian NDV isolates have a within-group genetic distance of 10.16% and a between-group genetic distance of 25.1% (Table 2). These isolates are grouped for ease of presentation as published by authors: group1 (sequences characterized in this study from the central part of the country), group 2 from the central part of Ethiopia, ....

Lohmann Animal Health , Office International Des Epizooties , National Veterinary Institute , Technelysium Pty Ltd , National Veterinary , Hemagglutination Inhibition , Pathogenicity Index , Diagnostic Tests , Terrestrial Animals , Gel Extraction Kit , Cycle Sequencing Kit , Applied Biosystems , Sigma Spin Post Reaction Clean Up Columns , Sanger Sequencer , Chromas Lite , Molecular Evolutionary Genetics Analysis , Minimum Evolution Method , Amino Acid Substitutions , Fusion Proteins , Standard Error , Genetic Distance Within , Two Groups , Mean Genetic Distance , Std Error Shown Above , Diagonal Line , Between Ethiopian ,

Punicalagin may be a potent drug for rheumatoid arthritis


1
1Department of Nephrology, Kidney and Urology Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, ShenZhen, Guandong, People’s Republic of China;
2Department of Rheumatology, The First Affiliated Hospital of Jinan University, Guangzhou, Guandong, People’s Republic of China;
3Department of Rheumatology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guandong, People’s Republic of China
These authors contributed equally to this work
Background: The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural polyphenol extracted in pomegranate juice, which possesses antioxidant, anti-inflammatory and anti-tumor properties suggesting it may be a potent drug for RA therapy. However, there is paucity of information on its effect in RA. ....

United States , San Leandro , Eteläuomen Läi , San Diego , Thiazol Tetrazolium Cytotoxicity , Alpha Innotech , National Institutes Of Health , Jiancheng Bioengineering Institute , American College Of Rheumatology , Laboratory Animal , Cell Signaling Technology , Laboratory Animal Company , Ethics Committee , Technology Co , Us National Institutes Of Health , Nuclear Factor Kappa , American College , Clinical Research Ethics Committee , First Affiliated Hospital , Sun Yat Sen University , Animal Care , Imaging Kit , Pro Inflammation Cytokines , Assay Diluent , Wash Buffer , Healing Assay ,

Frontiers | Influence of High Pass Filter Settings on Motor Evoked Potentials


2Department of Neurology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
3Department of Neurology, Medical Faculty, Assiut University Hospital, Assiut, Egypt
Objective: Motor evoked potentials (MEP), obtained by transcranial magnetic stimulation (TMS) are a common tool in clinical research and diagnostic. Nevertheless, reports regarding the influence of filter settings on MEP are sparse. Here, we compared MEP amplitudes and signal to noise ratio (SNR) using multiple high pass filter (HPF) and notch filter settings.
Materials and Methods: Twenty healthy subjects were enrolled in the study. Recruitment curves were obtained with HPF settings varied at 10, 20, 50, and 100 Hz. The four HPF settings were tested both with and without 50 Hz active notch filter. Low pass filter was kept constant at 5 kHz. ....

United Kingdom , Eteläuomen Läi , Van Boxtel , Magstim Co , Department Of Neurology , Ethics Committee Of The Medical Faculty , Heinrich Heine University , Digitimer Ltd , University Hospital , I Fcn Committee , Helsinki Declaration World Medical Association , Software Cambridge Electronic Design , Ethics Committee , World Medical Association , Helsinki Declaration , Medical Faculty , Signal Software , Cambridge Electronic Design , Active Motor Threshold , First Dorsal Interosseous , General Estimating Equations , High Pass Filter , Low Pass Filter , Motor Evoked Potentials , Resting Motor Threshold , Standard Error ,