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This Scientist Is Auctioning Off His DNA and Says Yours is Valuable Too

This Scientist Is Auctioning Off His DNA and Says Yours is Valuable Too
medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.

East Sussex , United Kingdom , Brighton And Hove , United States , University Park , Elizabeth Ford , Forrest Briscoe , Jack Dorsey , Kamal Obbad , David Koepsell , George Church , Sussex Medical School , Penn State Smeal College Of Business , Longevity International , Nebula Genomics , Personal Genome , Penn State Smeal College , Tina Woods , Open Life Data Framework , Nyan Cat , கிழக்கு சசெக்ஸ் , ஒன்றுபட்டது கிஂக்டம் , பிரகாசமான மற்றும் ஹோவ் , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் பூங்கா , எலிசபெத் ஃபோர்ட் ,

Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study

Research Article
Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study
Jeanne Tie ,
Contributed equally to this work with:
Jeanne Tie,
Yuxuan Wang
Roles
Conceptualization,
Data curation,
Formal analysis,
Funding acquisition,
Investigation,
Methodology,
Project administration,
Resources,
Supervision,
Writing – original draft,
Writing – review & editing
Roles
Data curation,
Formal analysis,
Investigation,
Methodology,
Writing – review & editing
Affiliation
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medicine, Baltimore, Maryland, United States of America
⨯
Joshua Cohen,
Affiliation
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins ....

United States , Johns Hopkins University , Victorian Cancer Agency , National Institutes Of Health , John Templeton Foundation , R Foundation For Statistical Computing , Dk Ludwig Fund For Cancer Research , Creative Commons Attribution License , Supporting Information , Cancer Research , National Institutes , Thrive Earlier Detection , Personal Genome , Thrive Earlier , Personal Genome Diagnostics , Catalio Capital , Johns Hopkins , College Station , Statistical Computing , ஒன்றுபட்டது மாநிலங்களில் , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , ஜான் கோயில் அடித்தளம் , ர் அடித்தளம் க்கு புள்ளிவிவர கணினி , ட்கே லுட்விக் நிதி க்கு புற்றுநோய் ஆராய்ச்சி , துணை தகவல் ,

Mutant Gene-Targeted Immunotherapy Approach Developed

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This news release, issued by Johns Hopkins Medicine, describes a novel targeted immunotherapy approach. This new approach employs bispecific antibodies to treat cancer by eliciting a Tcell response against mutated p53. The researchers used the Highly Automated Macromolecular Crystallography (AMX) and Frontier Microfocusing Macromolecular Crystallography (FMX) beamlines to characterize the molecular structure of the proteins. AMX and FMX are beamlines at the National Synchrotron Light Source II (NSLS-II) a U.S. Department of Energy (DOE) Office of Science User Facility at Brookhaven National Laboratory. NSLS-II offers a comprehensive suite of life science research capabilities. Johns Hopkins media contacts: Amy Mone, 410-614-2915, [email protected], or Valerie Mehl, 410-614-2916, [email protected]. Brookhaven Lab media contacts: Cara Laasch, 631-344-8458, [email protected] or Peter Genzer, 631-344-3174, [email protected]. ....

United States , Michaelb Murphy , Shibin Zhou , Valerie Mehl , Emily Han , Nickolas Papadopoulos , Michael Hwang , Evangeline Watson , Katharine Wright , Astra Zeneca Medimmune Amplimmune , Katharinem Wright , Yana Li , Elizabeth Cook , Patricka Brown , Gabriel Ghiaur , Bristol Myers Squibb , Bert Vogelstein , Kenneth Kinzler , Suman Paul , P Aitana Azurmendi , Sandra Gabelli , Chetan Bettegowda , Chung Hsiue , Michelles Miller , Andrew Skora , Sarahr Dinapoli ,

Cancer immunotherapy approach targets common genetic alteration

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IMAGE: Novel cancer immunotherapy approach inverts a missing gene copy into an immune cell-activating signal.
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Credit: Elizabeth Cook
Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers. The approach, which stimulates an immune response against cells that are missing one gene copy, called loss of heterozygosity (LOH), was developed by researchers at the Ludwig Center, Lustgarten Laboratory and the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center.
Genes have two alleles, or copies, with one copy inherited from each parent. Cancer-related genetic alterations commonly involve the loss of one of these gene copies. ....

United States , Shibin Zhou , Emily Han , Nickolas Papadopoulos , Michael Hwang , Astrazeneca Medimmune Amplimmune , Jacqueline Douglass , Johns Hopkins , Alexander Pearlman , Sarah Dinapoli , Bert Vogelstein , Kenneth Kinzler , Suman Paul , Sandra Gabelli , Chetan Bettegowda , Maximilian Konig , Chung Hsiue , Johns Hopkins University , Commonwealth Fund , Bloomberg Kimmel Institute For Cancer Immunotherapy , Dk Ludwig Fund For Cancer Research , Johns Hopkins Kimmel Cancer Center , Bristol Myers Squibb , National Cancer Institute Grant , Dracen Pharmaceuticals , National Institutes Of Health ,

Targeting a neoantigen derived from a common TP53 mutation

Targeting a neoantigen derived from a common TP53 mutation
sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.

United States , Rock Springs , Retronectin Clontech , Heracle Biosoft , Bristol Myers Squibb , Trustain Fc , Hiload Superdex , Astra Zeneca Medimmune Amplimmune , Essen Bioscience , M Dal Molin , Johns Hopkins University , Commonwealth Fund , Bloomberg Kimmel Institute For Cancer Immunotherapy , Kit Zymo Research , National Synchrotron Light , Us Department Of Energy , Dk Ludwig Fund For Cancer Research , Tetramer Core Facility Emory University , National Synchrotron Light Source , Environmental Research , Jackson Laboratory , Dracen Pharmaceuticals , Ge Healthcare , Brookhaven National Laboratory , National Institute , Becton Dickinson ,