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Discovery and verification of extracellular microRNA biomarkers for diagnostic and prognostic assessment of preeclampsia at triage

Discovery and verification of extracellular microRNA biomarkers for diagnostic and prognostic assessment of preeclampsia at triage
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Epigenetic clock analysis of blood samples in drug-naive first-episode schizophrenia patients | BMC Psychiatry

Schizophrenia (SCZ) is a severe and chronic psychiatric disorder with premature age-related physiological changes. However, numerous previous studies examined the epigenetic age acceleration in SCZ patients and yielded inconclusive results. In this study, we propose to explore the epigenetic age acceleration in drug-naive first-episode SCZ (FSCZ) patients and investigate whether epigenetic age acceleration is associated with antipsychotic treatment, psychotic symptoms, cognition, and subcortical volumes. We assessed the epigenetic age in 38 drug-naive FSCZ patients and 38 healthy controls by using three independent clocks, including Horvath, Hannum and Levine algorithms. The epigenetic age measurements in SCZ patients were repeated after receiving 8 weeks risperidone monotherapy. Our findings showed significantly positive correlations between epigenetic ages assessed by three clocks and chronological age in both FSCZ patients and healthy controls. Compared with healthy controls, ....

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Zymo Research veröffentlicht Open-Source-Bioinformatik-Pipeline für die Erkennung von SARS-CoV-2-Varianten in Abwässern

Zymo Research veröffentlicht Open-Source-Bioinformatik-Pipeline für die Erkennung von SARS-CoV-2-Varianten in Abwässern
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Targeting a neoantigen derived from a common TP53 mutation

Targeting a neoantigen derived from a common TP53 mutation
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Zymo Research führt Environ COVID-19-Abwassertest zur Erkennung von SARS-CoV-2-Fällen und Varianten ein

Zymo Research führt Environ COVID-19-Abwassertest zur Erkennung von SARS-CoV-2-Fällen und Varianten ein
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