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BCAS3-C16orf70 complex is a new actor on the mammalian autophagic machinery

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IMAGE: The confocal microscopy image of cell induced mitophagy. Autophagic membranes engulf the damaged mitochondria. TOMM20 (blue) is mitochondrial outer membrane protein and WIPI2 (red) is well-known autophagy protein. BCAS3-C16orf70 (green).
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Credit: TMIMS
Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria. PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria, then ubiquitin chains are recognized as signals for autophagy degradation. Dysfunction of mitophagy causes a decrease in mitochondrial quality with overproduction of ROS, and is linked to neurodegenerative diseases like Parkinson s disease. ....

Life Science Research , Tokushima University , Institute Of Advanced Medical Sciences , Research Programs , University Of Tokushima , Takeda Science Foundation , Chieko Iwanaga Fund For Parkinson Disease Research , National Institute Of Advanced Industrial Science , Ubiquitin Project , Breast Carcinoma Amplified Sequence , National Institute , Advanced Industrial Science , Chieko Iwanaga Fund , Disease Research , Joint Usage , Joint Research Programs , Advanced Medical Sciences , Platform Project , Supporting Drug Discovery , Supporting Innovative Drug Discovery , Molecular Biology , Medicine Health , Biomedical Environmental Chemical Engineering , வாழ்க்கை அறிவியல் ஆராய்ச்சி , டோக்குஷிமா பல்கலைக்கழகம் , ஆராய்ச்சி ப்ரோக்ர்யாம்ஸ் ,

Looking for a natural way to regrow hair? Try chaga mushrooms

https://www.afinalwarning.com/470660.html
(Natural News)
Alopecia areata is a condition characterized by hair falling out in patches. Research suggests it is caused by the immune system attacking the hair follicles, causing them to shrink and slow down hair production. Because of this, alopecia is called an autoimmune disorder.
According to statistics, alopecia is a common autoimmune disorder that affects about 6.8 million people in the U.S. alone. One in five people who suffer from alopecia has a family member with the same condition. Hair loss, however, can vary from nothing more than a few patches to complete loss of hair on the scalp or the entire body. ....

Tokushima University , Natural News , Alternative Medicine , Herbal Medicine , Womens Health , Womens Health , Anti Alopecia , Chaga Mushrooms , Good Health , Hair Growth , Hair Loss , Natural Cures , Natural Medicine , டோக்குஷிமா பல்கலைக்கழகம் , இயற்கை செய்தி , மாற்று மருந்து , மூலிகை மருந்து , ஆண்கள் ஆரோக்கியம் , பெண்கள் ஆரோக்கியம் , எதிர்ப்பு அலோபீசியா , சாகா காளான்கள் , நல்ல ஆரோக்கியம் , முடி வளர்ச்சி , முடி இழப்பு , இயற்கை குணப்படுத்துகிறது , இயற்கை மருந்து ,

Welby、糖尿病管理をAIで支援　音声で助言

Welby、糖尿病管理をAIで支援　音声で助言
nikkei.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nikkei.com Daily Mail and Mail on Sunday newspapers.

Justin Welby , Tokushima University , Tokushima University Hospital , ஜஸ்டின் வெல்பி , டோக்குஷிமா பல்கலைக்கழகம் , டோக்குஷிமா பல்கலைக்கழகம் மருத்துவமனை ,

About half of Japan residents experiencing serious stress amid virus crisis: survey

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About half of Japan residents experiencing serious stress amid virus crisis: survey
The Mainichi
© The Mainichi
People are seen walking in the Ginza district in Tokyo s Chuo Ward on Jan. 9, 2021, during the first weekend following the second declaration of a state of emergency in Japan. (Mainichi/Toshiki Miyama)
TOKYO A survey targeting residents of seven prefectures including Tokyo and Osaka found that about half of respondents are facing serious stress in their lives amid the coronavirus pandemic, as some individuals are staying at home persistently while others have gone out after growing tired from being confined indoors.
As the second state of emergency to stem coronavirus infections in Japan has been extended, the public will be asked to continue to refrain from nonessential and nonurgent outings, not to mention drinking out, in order to reinforce anti-infection measures. ....

Masako Miura , Ayumu Iwasaki , Tetsuya Yamamoto , Yongho Lee , Osaka University , Tokushima University , Machida Resident Bureau , Science Environment News Department , Chuo Ward , Toshiki Miyama , Mainichi People , Environment News Department , சகோ மிீுர , ஒசகக பல்கலைக்கழகம் , டோக்குஷிமா பல்கலைக்கழகம் , மச்சிடா குடியிருப்பாளர் பணியகம் , அறிவியல் சூழல் செய்தி துறை , சுோ வார்டு , சூழல் செய்தி துறை ,

Redefining Fluorescence Lifetime Imaging Microscopy

Redefining Fluorescence Lifetime Imaging Microscopy
Image Credit: Micha Weber/Shutterstock.com
Conventional fluorescence lifetime imaging microscopy (FLIM) relies on point-to-point scanning of a tightly focused illumination beam across the sample to form an image, impeding rapid imaging. To overcome this limitation, researchers from Japan and the USA have developed scan-less wide-field imaging methods that can image fluorescence lifetime at unprecedented speeds and capture ultrafast transient phenomena relevant to biomedical research and life sciences.
FLIM is an imaging technique that creates spatially resolved images of a fluorophore (fluorescent molecule used as a marker) lifetime. The fluorescence lifetime is an intrinsic property of the fluorophore, which describes, on average, how rapidly the fluorophore s excited state decays. ....

United States , Takeshi Yasui , Micha Weber Shutterstock , Cvetelin Vasilev , Tokushima University , Photonics At Tokushima University , Phd Feb , Conventional Fluorescence , Fluorescence Lifetime Measurements , Entire Sample , New Method , Fluorescence Microscopy , Technique Increases Effectiveness , Fluorescence Lifetime , Fluorescence Lifetime Imaging Microscopy , ஒன்றுபட்டது மாநிலங்களில் , டோக்குஷிமா பல்கலைக்கழகம் , ஃபோட்டானிக்ஸ் இல் டோக்குஷிமா பல்கலைக்கழகம் , ஃப்ட் ஃபெப் , முழு மாதிரி , புதியது முறை ,