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Study revises understanding of cancer metabolism

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IMAGE: (left to right) Kimryn Rathmell, Bradley Reinfeld, Matthew Madden and Jeffrey Rathmell have discovered that immune cells not cancer cells are the major glucose consumers in the tumor.
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Credit: Susan Urmy/VUMC
Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.
Instead, non-cancer cells in a tumor primarily immune cells called macrophages have the highest glucose uptake, the group reported April 7 in the journal ....

United States , Charles Manning , Christopher Williams , Bradley Reinfeld , Matthew Vander Heiden , Matthew Madden , Otto Warburg , W Kimryn Rathmell , Alexander Muir , Rachelle Johnson , David Merryman , Jeff Rathmell , Matthew Wilson , Hughj Morgan , Jeffrey Rathmell , Kimryn Rathmell , Colitis Foundation , American Heart Association , National Institutes Of Health , American Association For Cancer Research , Scientist Training Program , Koch Institute For Integrative Cancer Research , Vanderbilt Center , Us Department Of Veterans Affairs , University Of Chicago , Department Of Medicine ,

Fantasy Land

Fantasy Land
photograph courtesy visit south walton
The Dolphin Reef is one of four artificial reefs created by the nonprofit South Walton Artificial Reef Foundation to provide havens for sea life and destinations for snorkelers. Other reefs are shaped like a seahorse, a sea turtle, and a cobia fish.
This isnât the Gulf Coast of your childhood. Sure, the pristine, white beaches and quiet, turquoise waters have always been there. But, for most of the twentieth century, Floridaâs major tourist destinations were concentrated in the southern part of the state. There, travelers flocked to the glitz of Miamiâs South Beach, the spring break mecca of Fort Lauderdale, the roar of racing-obsessed Daytona, and the history of Cape Canaveral and the Space Coast. Along the Panhandleâs Gulf Coast, there wasnât much between Panama City and Pensacola except seagulls and fishing boats. ....

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