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A vital tool to study virus evolution in the test tube

Variants of viruses, such as that causing COVID-19, can now be quickly studied in the laboratory, even before they emerge in nature and become a major public health challenge.The University of Queensland, QIMR Berghofer Medical Research Institute, Pe ....

South Africa , United Kingdom , South African , Delta Indian , Jason Mackenzie , Daniel Watterson , Fasseli Coulibaly , Troy Hall , Andreas Suhrbier , Paul Young , Jody Hobson Peters , Alexander Khromykh , Frederick Moore , Berghofer Medical Research Institute , Nature Communications , Queensland Health , Monash University , University Of Queensland , Peter Doherty Institute For Infection , Medical Research Institute , Peter Doherty Institute , Professor Alexander Khromykh , Associate Professor Daniel Watterson , Professor Paul Young , Professor Roy Hall , Professor Jason Mackenzie ,

Chimeric viruses unearth hidden gems in dengue virus structure

In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as pocket factors as new therapeutic targets. ....

South Australia , Joshua Hardy , Daniel Watterson , Wendy Smith , Biomedicine Discovery Institute At Monash University , Nature Communications , Monash University , University Of Queensland , Monash Biomedicine Discovery Institute At University , Ramaciotti Centre For Cryo , Electron Microscopy At Monash University , Associate Professor Fass , Associate Professor Daniel Watterson , Ramaciotti Centre , Cryo Electron Microscopy , Associate Professor , Professor Coulibaly , Biomedicine Discovery Institute , Monash Biomedicine Discovery Institute , Cardiovascular Disease , Stem Cells , Media Enquiries , Manager Monash University , Molecular Biology , Infectious Emerging Diseases , தெற்கு ஆஸ்திரேலியா ,

Scientists use an original approach to resolve the 3D structure of flaviviruses

In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic targets. ....

South Australia , Daniel Watterson , Emily Henderson , Nature Communications , Monash University , University Of Queensland , Ramaciotti Centre For Cryo , Electron Microscopy At Monash University , Associate Professor Fass , Associate Professor Daniel Watterson , Ramaciotti Centre , Cryo Electron Microscopy , Associate Professor , Yellow Fever , தெற்கு ஆஸ்திரேலியா , டேனியல் வாட்டர்சன் , எமிலி ஹென்டர்சன் , இயற்கை தகவல்தொடர்புகள் , மோனாஷ் பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் குயின்ஸ்லாந்து , இணை ப்ரொஃபெஸர் பாஸ்ஸ் , க்ரியோ எதிர் மின்னணு நுண்ணோக்கி , இணை ப்ரொஃபெஸர் ,

Study reveals the first complete 3D molecular structure of immature flavivirus

Better designed vaccines for insect-spread viruses like dengue and Zika are likely after researchers discovered models of immature flavivirus particles were originally misinterpreted. ....

South Australia , Daniel Watterson , Emily Henderson , Monash University , University Of Queensland , Monash Ramaciotti Centre For Cryo , Associate Professor Daniel Watterson , Associate Professor , Ramaciotti Centre , Cryo Electron Microscopy , Associate Professor Fass , Electron Microscopy , தெற்கு ஆஸ்திரேலியா , டேனியல் வாட்டர்சன் , எமிலி ஹென்டர்சன் , மோனாஷ் பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் குயின்ஸ்லாந்து , இணை ப்ரொஃபெஸர் , க்ரியோ எதிர் மின்னணு நுண்ணோக்கி , இணை ப்ரொஃபெஸர் பாஸ்ஸ் , எதிர் மின்னணு ,

Scientists rewrite the genesis of mosquito-borne viruses

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IMAGE: Cryo-electron microscopy reconstruction of Binjari virus. The projecting spikes are a typical feature of immature flaviviruses such as dengue virus but reveal an unexpected organization.
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Credit: Associate Professor Fasseli Coulibaly
Better designed vaccines for insect-spread viruses like dengue and Zika are likely after researchers discovered models of immature flavivirus particles were originally misinterpreted.
Researchers from The University of Queensland and Monash University have now determined the first complete 3D molecular structure of the immature flavivirus, revealing an unexpected organisation.
UQ researcher Associate Professor Daniel Watterson said the team was studying the insect-specific Binjari virus when they made the discovery. ....

South Australia , Joshua Hardy , Daniel Watterson , Monash University , University Of Queensland , Monash Biomedicine Discovery Institute , Monash Ramaciotti Centre For Cryo , Associate Professor Daniel Watterson , Ramaciotti Centre , Cryo Electron Microscopy , Associate Professor Fass , Science Advances , Monash Biomedicine Discovery , Cell Biology , Medicine Health , Infectious Emerging Diseases , Public Health , Disease In The Developing World , தெற்கு ஆஸ்திரேலியா , ஜோஷுவா ஹார்டி , டேனியல் வாட்டர்சன் , மோனாஷ் பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் குயின்ஸ்லாந்து , க்ரியோ எதிர் மின்னணு நுண்ணோக்கி , இணை ப்ரொஃபெஸர் பாஸ்ஸ் , உயிரி தொழில்நுட்பவியல் ,