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University of Bristol: Accurate Aging of Wild Animals Thanks to First Epigenetic Clock for Bats

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New research by the University of Bristol as part of a team led by the University of Maryland (UMD) identifies age-related changes to DNA, revealing longevity-related differences among bat species.
The study found that DNA from tissue samples can be used to accurately predict the age of bats in the wild. The study also showed age-related changes to the DNA of long-lived species are different from those in short-lived species, especially in regions of the genome near genes associated with cancer and immunity. This work provides new insight into causes of age-related declines.
This is the first research paper to show that animals in the wild can be accurately aged using an epigenetic clock, which predicts age based on specific changes to DNA. This work provides a new tool for biologists studying animals in the wild. In addition, the results provide insight into possible mechanisms behind the exceptional longevity of many bat species. The study was published on Marc ....

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Accurate aging of wild animals thanks to first epigenetic clock for bats

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IMAGE: UMD-led study revealed age-related changes to the DNA of bats related to longevity. Clockwise from top left: common vampire bat (G. Wilkinson), greater horseshoe bat (G. Jones), velvety free-tailed bat.
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Credit: G. Wilkinson, G. Jones, S. Puechmaille, M. Tschapka
A new study led by University of Maryland and UCLA researchers found that DNA from tissue samples can be used to accurately predict the age of bats in the wild. The study also showed age-related changes to the DNA of long-lived species are different from those in short-lived species, especially in regions of the genome near genes associated with cancer and immunity. This work provides new insight into causes of age-related declines. ....

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