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Sex cells in parasites are doing their own thing


Credit: Dr Lori Peacock
Researchers at the University of Bristol have discovered how microbes responsible for human African sleeping sickness produce sex cells.
In these single-celled parasites, known as trypanosomes, each reproductive cell splits off in turn from the parental germline cell, which is responsible for passing on genes. Conventional germline cells divide twice to produce all four sex cells - or gametes - simultaneously. In humans four sperms are produced from a single germline cell. So, these strange parasite cells are doing their own thing rather than sticking to the biology rulebook.
Trypanosome cell biology has already revealed several curious features. They have two unique intracellular structures - the kinetoplast, a network of circular DNA and the glycosome, a membrane-enclosed organelle that contains the glycolytic enzymes. They don t follow the central dogma that DNA is faithfully transcribed into RNA, but will go back and edit some of the RNA tr ....

City Of , United Kingdom , Chris Kay , Lori Peacock , Wendy Gibson , Mark Carrington , Mick Bailey , Chloe Farren , University Of Cambridge , University Of Bristol School Biological Sciences , Communications Biology , Bristol School Of Biological Sciences , School Of Veterinary Sciences , University Of Bristol , Biological Sciences , Veterinary Sciences , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , கிறிஸ் காய் , லோரி மயில் , வெண்டி கிப்சன் , குறி கேரிங்டன் , மிக் பெய்லி , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் பள்ளி உயிரியல் அறிவியல் , தகவல்தொடர்புகள் உயிரியல் ,

Sex cells in parasites are doing their own thing


Trypanosome cell during meiosis producing the first gamete
Dr Lori Peacock
Dr Lori Peacock
Cartoon showing large nucleus in blue and two smaller nuclei in pale blue and kinetoplasts in dark blue
Dr Lori Peacock
Researchers at the University of Bristol have discovered how microbes responsible for human African sleeping sickness produce sex cells.
In these single-celled parasites, known as trypanosomes, each reproductive cell splits off in turn from the parental germline cell, which is responsible for passing on genes. Conventional germline cells divide twice to produce all four sex cells – or gametes – simultaneously. In humans four sperms are produced from a single germline cell. So, these strange parasite cells are doing their own thing rather than sticking to the biology rulebook. ....

City Of , United Kingdom , Chris Kay , Mark Carrington , Wendy Gibson , Lori Peacock , Mick Bailey , Chloe Farren , University Of Cambridge , University Of Bristol School Biological Sciences , Communications Biology , Bristol School Of Biological Sciences , School Of Veterinary Sciences , University Of Bristol , Biological Sciences , Veterinary Sciences , University Of Cambridge , Drug Resistance , Cell Biology , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , கிறிஸ் காய் , குறி கேரிங்டன் , வெண்டி கிப்சன் , லோரி மயில் , மிக் பெய்லி ,