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Dangers in giving magnesium sulfate intravenously to horses highlighted in study


Horsetalk.co.nz
Dangers in giving magnesium sulfate intravenously to horses highlighted in study
Intravenous administration of magnesium sulfate to horses to provide a competitive edge is a nefarious and dangerous practice, say researchers.
Magnesium is an essential macroelement involved in many physiological processes.
In equine medicine, intravenous magnesium sulfate is used to treat heart rhythm irregularities, neurological disorders, low magnesium levels in the blood that might arise during critical illness, and for low levels of calcium in the blood which are not responding to other treatments.
However, more recently, intravenous magnesium has been used in equine events as a calming and performance-enhancing agent, with the ultimate goal of giving a competitive edge to horses that receive it. It is a practice forbidden at FEI events under the international governing body’s anti-doping rules because of its calming and metabolic effects. ....

Stephen Schumacher , Jeffrey Lakritz , Ramiro Toribio , Teresa Burns , Ahmed Kamr , Alicia Bertone , Researchers At Ohio State University , Ohio State University , Creative Commons License , ஸ்டீபன் ஷூமேக்கர் , ஜெஃப்ரி லக்ரிட்ஸ் , ரெமிரொ டோரிபியோ , தெரசா தீக்காயங்கள் , அலிசியா பெர்டோன் , ஆராய்ச்சியாளர்கள் இல் ஓஹியோ நிலை பல்கலைக்கழகம் , ஓஹியோ நிலை பல்கலைக்கழகம் , படைப்பு காமன்ஸ் உரிமம் ,

Nanobodies may be the key to blocking tick-borne bacterial infection


Nanobodies may be the key to blocking tick-borne bacterial infection
Tiny molecules called nanobodies, which can be designed to mimic antibody structures and functions, may be the key to blocking a tick-borne bacterial infection that remains out of reach of almost all antibiotics, new research suggests.
The infection is called human monocytic ehrlichiosis, and is one of the most prevalent and potentially life-threatening tick-borne diseases in the United States. The disease initially causes flu-like symptoms common to many illnesses, and in rare cases can be fatal if left untreated.
Most antibiotics can t build up in high enough concentrations to kill the infection-causing bacteria, Ehrlichia chaffeensis, because the microbes live in and multiply inside human immune cells. Commonly known bacterial pathogens like Streptococcus and E. coli do their infectious damage outside of hosts cells. ....

United States , Ohio State University , Dehua Pei , Jeffrey Lakritz , Yasuko Rikihisa , Emily Henderson , Proceedings Of The National Academy Sciences , State University , National Academy , Ohio State , E Coli , ஒன்றுபட்டது மாநிலங்களில் , ஓஹியோ நிலை பல்கலைக்கழகம் , ஜெஃப்ரி லக்ரிட்ஸ் , எமிலி ஹென்டர்சன் , நிலை பல்கலைக்கழகம் , தேசிய கலைக்கழகம் , ஓஹியோ நிலை , ஏ கோலி ,

Using nanobodies to block a tick-borne bacterial infection


Using nanobodies to block a tick-borne bacterial infection
Tiny molecules called nanobodies, which can be designed to mimic antibody structures and functions, may be the key to blocking a tick-borne bacterial infection that remains out of reach of almost all antibiotics, new research suggests.
The infection is called human monocytic ehrlichiosis, and is one of the most prevalent and potentially life-threatening tick-borne diseases in the United States. The disease initially causes flu-like symptoms common to many illnesses, and in rare cases can be fatal if left untreated.
Most antibiotics can’t build up in high enough concentrations to kill the infection-causing bacteria,  ....

United States , Ohio State University , Mingqun Lin , Hongyan Liu , Khemraj Budachetri , Ashweta Sahni , Dehua Pei , Jeffrey Lakritz , Libo Hou , Qi Yan , Yasuko Rikihisa , Wenqing Zhang , Ching Han , Proceedings Of The National Academy Sciences , National Institutes Of Health , State University , National Academy , Ohio State , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , ஓஹியோ நிலை பல்கலைக்கழகம் , ஜெஃப்ரி லக்ரிட்ஸ் , குய் யான் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , நிலை பல்கலைக்கழகம் , தேசிய கலைக்கழகம் ,

Study uses nanobodies to block tick-borne bacterial infection


Study uses nanobodies to block tick-borne bacterial infection
ANI |
Updated: Apr 28, 2021 23:28 IST
Washington [US], April 28 (ANI): The findings of recent research suggest that tiny molecules called nanobodies, which can be designed to mimic antibody structures and functions, might be the key to blocking a tick-borne bacterial infection that remains out of reach of almost all antibiotics.
The research is published this week in Proceedings of the National Academy of Sciences. The infection is called human monocytic ehrlichiosis and is one of the most prevalent and potentially life-threatening tick-borne diseases in the United States. The disease initially causes flu-like symptoms common to many illnesses, and in rare cases can be fatal if left untreated. ....

United States , Ohio State University , Dehua Pei , Jeffrey Lakritz , Yasuko Rikihisa , Proceedings Of The National Academy Sciences , National Academy , State University , Ohio State , ஒன்றுபட்டது மாநிலங்களில் , ஓஹியோ நிலை பல்கலைக்கழகம் , ஜெஃப்ரி லக்ரிட்ஸ் , தேசிய கலைக்கழகம் , நிலை பல்கலைக்கழகம் , ஓஹியோ நிலை ,