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Novartis' canakinumab misses the mark in previously treated NSCLC

Novartis' canakinumab misses the mark in previously treated NSCLC
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John Tsai , Merck Co Keytruda , European Medicines Agency , ஜான் ட்‌ஸை ,

Novartis Pharma AG: Novartis provides update on Phase III study evaluating canakinumab (ACZ885) as second or third-line treatment in combination with chemotherapy in non-small cell lung cancer


Novartis Pharma AG: Novartis provides update on Phase III study evaluating canakinumab (ACZ885) as second or third-line treatment in combination with chemotherapy in non-small cell lung cancer
1
non-small cell lung cancer
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1 beta (IL-1ß) in pro-tumor inflammation i
n lung cancer, with multiple clinical trials investigating
canakinumab in
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Basel, March 9, 2021 - Novartis announced today the Phase III CANOPY-2 study evaluating canakinumab (ACZ885), an inhibitor of interleukin-1beta (IL-1ß), in combination with the chemotherapy agent docetaxel, did not meet its primary endpoint of overall survival (OS)
1. The trial was conducted among 237 adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose disease progressed while on or after previous platinum-based chemotherapy and PD-(L)1 inhibitor immunotherapy ....

United States , Isabella Zinck , Thomas Hungerbuehler , Samir Shah , Mary Curtin Creaser , Biochim Biophys Acta , Julie Masow , Sloan Simpson , John Tsai , Global Oncology Communications , American Joint Committee On Cancer , Head Of Global Drug Development , World Health Organization , Novartis Us External Communications , Exchange Commission , Strategy Financial Communications , National Comprehensive Cancer Network Guidelines , American Cancer Society , Global Drug Development , Chief Medical Officer , Without Canakinumab , Previously Untreated Locally Advanced , Metastatic Non Squamous , Adjuvant Therapy , Adult Subjects With Stages , Evaluating Efficacy ,