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COMING SOON: EV-302/KEYNOTE-A39: Open-Label, Randomized Phase 3 Study of Enfortumab Vedotin in Combination with Pembrolizumab vs Chemotherapy in Previously Untreated Locally Advanced or Metastatic Urothelial Carcinoma

Terence Friedlander, MD, shares a look at an upcoming program reviewing recent, significant data from the EV-302/KEYNOTE-A39 study. ....

Enfortumab Vedotin , Randomized Phase , Previously Untreated Locally Advanced , Metastatic Urothelial , Urothelial Carcinoma , Urothelial Cancer , Advanced Or Metastatic Urothelial Carcinoma , Ev 302 , Keynote A39 ,

Novartis Pharma AG: Novartis provides update on Phase III study evaluating canakinumab (ACZ885) as second or third-line treatment in combination with chemotherapy in non-small cell lung cancer

Novartis Pharma AG: Novartis provides update on Phase III study evaluating canakinumab (ACZ885) as second or third-line treatment in combination with chemotherapy in non-small cell lung cancer
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Basel, March 9, 2021 - Novartis announced today the Phase III CANOPY-2 study evaluating canakinumab (ACZ885), an inhibitor of interleukin-1beta (IL-1ß), in combination with the chemotherapy agent docetaxel, did not meet its primary endpoint of overall survival (OS)
1. The trial was conducted among 237 adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose disease progressed while on or after previous platinum-based chemotherapy and PD-(L)1 inhibitor immunotherapy ....

United States , Isabella Zinck , Thomas Hungerbuehler , Samir Shah , Mary Curtin Creaser , Biochim Biophys Acta , Julie Masow , Sloan Simpson , John Tsai , Global Oncology Communications , American Joint Committee On Cancer , Head Of Global Drug Development , World Health Organization , Novartis Us External Communications , Exchange Commission , Strategy Financial Communications , National Comprehensive Cancer Network Guidelines , American Cancer Society , Global Drug Development , Chief Medical Officer , Without Canakinumab , Previously Untreated Locally Advanced , Metastatic Non Squamous , Adjuvant Therapy , Adult Subjects With Stages , Evaluating Efficacy ,

Novartis provides update on Phase III study evaluating canakinumab (ACZ885) as second or third-line treatment in combination with chemotherapy in non-small cell lung cancer

19. More people die of lung cancer every year than any other cancer type
11. Novartis is committed to developing best-in-class treatments for lung cancer patients around the world. With a focus on both targeted, personalized medicine and the role of newer, immuno-oncology therapies, the lung cancer drug development program at Novartis is among the most robust in the industry. With research activities informed by long-term relationships with leading lung cancer thought leaders and patient advocates, Novartis is focused on reimagining the treatment of lung cancer.
Disclaimer
This press release contains forward-looking statements within the meaning of the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements can generally be identified by words such as “potential,” “potentially,” “can,” “will,” “expected,” “committed,” “evaluating,” “continue,” “ongoing,” “approximately,” or similar terms, ....

United States , Isabella Zinck , Thomas Hungerbuehler , Samir Shah , Mary Curtin Creaser , Biochim Biophys Acta , Julie Masow , Sloan Simpson , John Tsai , Global Oncology Communications , American Joint Committee On Cancer , Head Of Global Drug Development , World Health Organization , Exchange Commission , Strategy Financial Communications , National Comprehensive Cancer Network Guidelines , American Cancer Society , Global Drug Development , Chief Medical Officer , Lung Cancer , Without Canakinumab , Previously Untreated Locally Advanced , Metastatic Non Squamous , Adjuvant Therapy , Adult Subjects With Stages , Evaluating Efficacy ,