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Why did Yale dismiss Bandy X. Lee? - The Boston Globe


Why did Yale dismiss Bandy X. Lee?
In dismissing Dr. Bandy X. Lee, the university cited the Goldwater Rule, which has been shown to be scientifically untenable.
By Leonard L. Glass, Edwin B. Fisher, and Lance DodesUpdated April 14, 2021, 12:59 p.m.
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Yale University campus in New Haven, Conn.SASHA RUDENSKY/NYT
Recent news that Yale University declined to reappoint Dr. Bandy X. Lee as a professor in the psychiatry department has stirred broad concern in the mental health care community and academic world. Yale’s disciplinary actions against Lee arose in the wake of a complaint from Alan Dershowitz, at the time an adviser to Donald Trump’s impeachment defense. Echoing Dershowitz’s complaint, Yale’s actions against Lee were explicitly grounded on her alleged violation of the widely disputed Goldwater Rule. The decision ultimately to terminate her appointment fueled letters of protest, including one from the three of us. ....

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Leptin puts the brakes on eating via novel neurocircuit


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Credit: Elsevier, 2021
Philadelphia, April 6, 2021 - Since the discovery of leptin in the 1990s, researchers have wondered, how does leptin, a hormone made by body fat, suppress appetite? Despite tremendous gains in the intervening three decades, many questions still remain. Now, a new study in mice describes novel neurocircuitry between midbrain structures that control feeding behaviors that are under modulatory control by leptin. The study appears in
John Krystal, MD, Editor of Biological Psychiatry, said of the findings, Omrani and colleagues shed light on how, in non-obese animals, leptin puts the brakes on overeating.
Leptin acts as a critical link between the body and the brain, providing information about metabolic state and exerting control over energy balance. The importance of leptin is illustrated by the finding that animals deficient for leptin rapidly become obese without its regulatory stop on feeding behavior. ....

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