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Nationwide "Rise Above COVID" Movement Seeks to Represent the Country's Diversity in COVID-19 Clinical Trial - Los Angeles Sentinel | Los Angeles Sentinel


Nationwide “Rise Above COVID” Movement Seeks to Represent the Country’s Diversity in COVID-19 Clinical Trial
By Special to the Sentinel
Published May 6, 2021
Tony Wafford, member of the Rise Above COVID Community Advisory Board
Rise Above COVID is raising awareness of ACTIV-2, a nationwide clinical trial to evaluate potential treatments for early COVID-19. The study is enrolling adults within eight days of experiencing symptoms and 10 days of their positive COVID-19 test result. ACTIV-2 is working to enroll people of color to ensure that the nation’s diverse population is represented in the trial.
The U.S. Black population has experienced 10 percent more COVID-19 cases, nearly 300 percent more hospitalizations, and 90 percent more deaths (CDC, March 2021) than non-Hispanic whites. Historically, the Black community has had the lowest clinical trial participation rates of any racial group and only 8 percent participation in clinical trials of drugs that w ....

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Large NIH clinical trial will test polyclonal antibody therapeutic for COVID-19


HIN
A Phase 2/3 trial to evaluate a new fully-human polyclonal antibody therapeutic targeted to SARS-CoV-2, called SAB-185, has begun enrolling non-hospitalized people with mild or moderate cases of COVID-19. The trial, ACTIV-2, is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The therapeutic was developed by SAB Biotherapeutics, Inc. (Sioux Falls, South Dakota).
NIH’s Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) program is a public-private partnership to develop a coordinated research strategy for speeding development of the most promising treatments and vaccine candidates. ACTIV-2 is a master protocol designed for evaluating multiple investigational agents in adults with mild-to-moderate COVID-19 who are not hospitalized. Led by the NIAID-funded AIDS Clinical Trials Group (ACTG) and supported by PPD (Wilmington, North Carolina), a global contract research organization t ....

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