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Asthma drug budesonide shortens recovery time in non-hospitalised patients with COVID-19


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Early treatment with inhaled budesonide shortens recovery time by a median of three days in patients with COVID-19 who are at higher risk of more severe illness and are treated in the community, finds Oxford University’s Platform Randomised Trial of Interventions against COVID-19 in Older People (PRINCIPLE) trial.
PRINCIPLE is the world’s largest Phase 3 platform randomised controlled trial to find clear evidence of an effective COVID-19 treatment for use in the community that can significantly shorten recovery time. As one of the UK Government’s national priority platform trials, findings from PRINCIPLE have potential to change how COVID-19 is treated in its early stages in non-hospital, community settings in the UK and internationally. ....

United Kingdom , Fiona Watt , Richard Hobbs , Mona Bafadhel , Chris Butler , Trial Steering Committee , United Kingdom Research , University Of Oxford , Oxford University Platform Randomised Trial Of Interventions , National Institute For Health Research , Therapeutics Task , Department Of Health , Oxford University Nuffield Department Of Medicine , Research Council , Oxford University , Platform Randomised Trial , Older People , United Kingdom Government , Chief Investigator , Professor Chris Butler , South Wales , Primary Care , Nuffield Department , Primary Care Health Sciences , United Kingdom Wide , Therapeutics Taskforce ,

Asthma drug budesonide shortens recovery time in non-hospitalised patients with COVID-19


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Asthma drug budesonide shortens recovery time in non-hospitalised patients with COVID-19
Inhaled budesonide, a common corticosteroid, is the first widely available, inexpensive drug found to shorten recovery times in COVID-19 patients aged over 50 who are treated at home and in other community settings, reports the UK’s PRINCIPLE trial in 1,779 participants.
Early treatment with inhaled budesonide shortens recovery time by a median of three days in patients with COVID-19 who are at higher risk of more severe illness and are treated in the community, finds Oxford University’s Platform Randomised Trial of Interventions against COVID-19 in Older People (PRINCIPLE) trial. ....

United Kingdom , Fiona Watt , Richard Hobbs , Chris Butler , Mona Bafadhel , Trial Steering Committee , United Kingdom Research , University Of Oxford , Oxford University Platform Randomised Trial Of Interventions , National Institute For Health Research , Therapeutics Task , Department Of Health , Oxford University Nuffield Department Of Medicine , Research Council , Oxford University , Platform Randomised Trial , Older People , United Kingdom Government , Chief Investigator , Professor Chris Butler , South Wales , Primary Care , Nuffield Department , Primary Care Health Sciences , United Kingdom Wide , Therapeutics Taskforce ,