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Dannielle Engle awarded prestigious pancreatic cancer research grant

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IMAGE: Salk Assistant Professor Dannielle Engle was selected as the first recipient of the Lustgarten Foundation-AACR Career Development Award for Pancreatic Cancer Research in Honor of Ruth Bader Ginsburg, the late.
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Credit: Salk Institute
LA JOLLA (April 12, 2021) Salk Assistant Professor Dannielle Engle was selected as the first recipient of the Lustgarten Foundation-AACR Career Development Award for Pancreatic Cancer Research in Honor of Ruth Bader Ginsburg, the late Supreme Court Justice and women s rights pioneer.
Engle will receive $300,000 to fund her pancreatic cancer research, which is focused on understanding how we can intercept the signals causing pancreatic cancer to metastasize and become so deadly. The award, along with a similar grant honoring Rep. John Lewis, was announced Sunday, April 11, during AACR s annual meeting. ....

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Parkinson's, cancer, and diabetes may all share one key factor

New insights into a biochemical pathway that drives Parkinson's may help scientists develop future treatments for type 2 diabetes and cancer. ....

Reuben Shaw , Salk Cancer Center , Science Advances , ரூபன் ஷா , சாள்க் புற்றுநோய் மையம் ,

Key Element Drives Parkinson's, Cancer, Type 2 Diabetes

Key Element Drives Parkinson's, Cancer, Type 2 Diabetes
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Portia Lombardo , Williamr Brody , Reuben Shaw , Retinopathydiabetesdiabetic Dietotitis Mediadiabetes , Salk Cancer Center , Professor Reuben Shaw , Science Advances , Chien Min Hung , Blood Glucose , Monitoring Of Blood Glucose , Insulin Delivery Devicesdiabetes , போர்ஶிய லோம்பார்டோ , ரூபன் ஷா , சாள்க் புற்றுநோய் மையம் , ப்ரொஃபெஸர் ரூபன் ஷா , சீன் நிமிடம் தொங்கவிடப்பட்டது ,

Parkinson's disease, type 2 diabetes, and cancer share the same pathway, shows study

Parkinson s disease, type 2 diabetes, and cancer share the same pathway, shows study
When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell s most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power stations that generate energy for the cell.
Now Salk researchers have discovered a direct link between a master sensor of cell stress and Parkin itself. The same pathway is also tied to type 2 diabetes and cancer, which could open a new avenue for treating all three diseases.
Our findings represent the earliest step in Parkin s alarm response that anyone s ever found by a long shot. All the other known biochemical events happen at one hour; we ve now found something that happens within five minutes, says Professor Reuben Shaw, director of the NCI-designated Salk Cancer Center and senior author of the new work, detailed in ....

Portia Lombardo , Williamr Brody , Reuben Shaw , Emily Henderson , Salk Cancer Center , Professor Reuben Shaw , Science Advances , Chien Min Hung , Salk Cancer , போர்ஶிய லோம்பார்டோ , ரூபன் ஷா , எமிலி ஹென்டர்சன் , சாள்க் புற்றுநோய் மையம் , ப்ரொஃபெஸர் ரூபன் ஷா , சீன் நிமிடம் தொங்கவிடப்பட்டது , சாள்க் புற்றுநோய் ,

Parkinson's, cancer, type 2 diabetes share a key element that drives disease

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IMAGE: Parkin protein (green signal) is in a different part of the cell than the mitochondria (red signal) at time 0 (left image) but then co-localizes with the mitochondria after 60.
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Credit: Salk Institute
LA JOLLA (April 7, 2021) When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell s most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power stations that generate energy for the cell. Now Salk researchers have discovered a direct link between a master sensor of cell stress and Parkin itself. The same pathway is also tied to type 2 diabetes and cancer, which could open a new avenue for treating all three diseases. ....

Portia Lombardo , Williamr Brody , Reuben Shaw , Salk Cancer Center , Professor Reuben Shaw , Science Advances , Chien Min Hung , போர்ஶிய லோம்பார்டோ , ரூபன் ஷா , சாள்க் புற்றுநோய் மையம் , ப்ரொஃபெஸர் ரூபன் ஷா , சீன் நிமிடம் தொங்கவிடப்பட்டது ,