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கொரோனா நிவாரணம்: EssEmm கார்ப்பரேஷன் 600 யூனிட் ஆக்ஸிஜன் செறிவூட்டிகள் நன்கொடை!

கொரோனா நிவாரணம்: EssEmm கார்ப்பரேஷன் 600 யூனிட் ஆக்ஸிஜன் செறிவூட்டிகள் நன்கொடை!
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Satish Nair , A Udhayanidhi Stalin , Director Satish Nair , Udhayanidhi Stalin , சத்தீஷ் நாயர் ,

ಬೆಂಗಳೂರಿನ 8 ಆಸ್ಪತ್ರೆಗಳಲ್ಲಿ 179 ಬ್ಲ್ಯಾಕ್ ಫಂಗಸ್ ಪ್ರಕರಣ ವರದಿ, 14 ಸಾವು

ಬೆಂಗಳೂರಿನ 8 ಆಸ್ಪತ್ರೆಗಳಲ್ಲಿ 179 ಬ್ಲ್ಯಾಕ್ ಫಂಗಸ್ ಪ್ರಕರಣ ವರದಿ, 14 ಸಾವು
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Piecing together the LanCL puzzle

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IMAGE: Removing the phosphate group from kinases can activate them, which can be problematic. LanCL adds glutathione to these kinases, after which they became deactivated.
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Credit: Wilfred van der Donk
Researchers from the Carl R. Woese Institute for Genomic Biology in collaboration with scientists at Oxford University have published a paper in
Cell reporting the function of LanCL proteins. These proteins are found in eukaryotic cells but their function was previously unknown. The study is the first step towards understanding the importance of these ubiquitous proteins.
Bacteria contain enzymes called LanC that are capable of producing small proteins called lanthipeptides, which are characterized by the addition of a thiol group to a modified serine or threonine amino acid. Similar proteins called LanC-like or LanCL have been found in different eukaryotic cells for decades, but their function was unknown. ....

United States , United Kingdom , Jie Chen , Benjamin Davis , Marie Sklodowska Curie , University Of Oxford , National Institutes Of Health , Head Of The Department Biochemistry , Department Of Biochemistry , Carlr Woese Institute For Genomic Biology , Sciences Research Council , Sciences Research Council United Kingdom Catalysis Hub , Felix Foundation , Oxford University , Howard Hughes Medical Institute , Genomic Biology , Howard Hughes Medical , Satish Nair , National Institutes , Biological Sciences Research Council , Physical Sciences Research Council , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , ஜிே சென் , பெஞ்சமின் டேவிஸ் , மேரி சகிலோதோவ்ஸ்க் கியூரி ,

Basic cell health systems wear down in Huntington's disease, analysis shows

Basic cell health systems wear down in Huntington’s disease, analysis shows
February 26, 2021MIT
A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis.
Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington’s disease may progress to advanced stages more because of a degradation of the cells’ health maintenance systems than because of increased damage from the disease pathology itself.
The analysis yielded a trove of specific gene networks governing molecular pathways that disease researchers may now be able to target to better sustain brain cell health amid the devastating neurodegenerative disorder, says co-senior author Myriam Heiman, associate professor in MIT’s Department of Brain and Cognitive Sciences and an investigator at The Picower In ....

Myriam Heiman , Mary Wertz , Christian Neri , Barbara Gris , Thomas Vogt , Jasmin Cevost , Lucile Megret , Jeff Aaronson , Satish Nair , Jim Rosinski , William Yang , Hilary Wilkinson , Broad Institute , University Of California At Los Angeles , Department Of Brain , National Institutes Of Health , Cognitive Sciences , Picower Institute For , Sorbonne Centre National De La Recherche Scientifique , Sorbonne Universit , Picower Institute , Centre National De La Recherche Scientifique , Los Angeles , National Institutes , மியிரியம் ஹெய்மன் , மேரி வேரத்ஜு ,

Basic cell health systems wear down in Huntington's disease, analysis shows

Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found. ....

Myriam Heiman , Mary Wertz , Christian Neri , Barbara Gris , Thomas Vogt , Jasmin Cevost , Lucile Megret , Jeff Aaronson , Satish Nair , Jim Rosinski , William Yang , Hilary Wilkinson , Broad Institute , University Of California At Los Angeles , Department Of Brain , National Institutes Of Health , Cognitive Sciences , Picower Institute For , Sorbonne Centre National De La Recherche Scientifique , Sorbonne Universit , Picower Institute , Centre National De La Recherche Scientifique , Los Angeles , National Institutes , University Of California , Immune Response ,