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The new store spans 1800 sq ft and has used fixtures and fittings recycled from previous shop fits. Craghoppers, which designs sustainable outdoor ....
Unfinished Business band leader Ed Miller spent years as an FBI agent, but what he always wanted to do was play rock n roll. After seeing The Beatles on The Ed Sullivan Show as an 11-year-old, he begged his parents for an electric guitar and practiced, practiced, practiced. He was in his first band by 14, and though he kept his hand in music, his law enforcement career eventually subsumed his music dreams. Then he retired from the FBI, started Unfinished Business in 2003, and they ve been going strong ever since . except for that pesky last 14 months or so. click to enlarge ....
Immuno-Oncology In Vitro Assays By Ben Tyrrell and Katie Chapple, Sartorius Stedim Biooutsource We offer a wide range of assay types and formats to characterize immune-oncology monoclonal antibodies (mAbs). In this application note, we discuss our recently developed assay format to characterize checkpoint inhibitor mAbs, specifically discussing those that target the PD-1 PD-L1 pathway. Targeting immune checkpoints such as the PD-1 PD-L1 pathway has proven in recent years to be an effective treatment approach resulting in a range of approved mAbs that bind PD-1 or its ligand PD-L1. The checkpoint inhibitor pathways continue to be an area of intensive research and development to bring other Mab treatments to the market. Characterizing the mechanism of action (MoA) of these molecules requires complex assays using primary cells because the MoA rely upon the interaction between T cells and antigen presenting cells. ....
60 Stabiliser suckler cows crossed to a Red Angus/Simmental-cross 700 Highlander ewes Farm rises to 260m above sea level Clay loam soil Insect protein An avian premix of vitamins and trace elements is supplemented with insects and worms as the birds follow a rotational grazing system behind cattle. Crucially, the wild insect protein helps to offset the removal of soya from the diet. “I believe this element of the diet is crucial to the flavour, and definitely helps in terms of protein requirements, but the feed ration my supplier has devised is a complete feed in itself.” Mr Chapple also grows multispecies leys and direct drills oats and barley; he is considering producing insects too. “If we can do that within the rules in this country that would be great, but there are some Defra regulations that restrict the use of insects,” he says. ....