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Precision oncology outfit Erasca joins the parade of San Diego IPOs this year


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Erasca, a biotechnology company pursuing precision oncology treatments to “erase cancer,” became San Diego’s newest publicly traded company late last week, raising $300 million in an upsized initial public stock offering.
The company, co-founded in 2018 by life sciences entrepreneur Dr. Jonathan Lim, becomes the 11
th local firm to go public so far this year. That’s approaching an annual record of 12 IPOs on U.S. markets for San Diego-based startups with five months to go in 2021.
Erasca sold 18.75 million shares at $16 per share. The stock began trading Friday on the Nasdaq exchange.
The company is targeting certain cancer-causing gene mutations. These mutations create a form of protein that continually tells cancer cells that it is okay to multiply. ....

San Diego , United States , Roche Genentech , Kevan Shokat , Jonathan Lim , San Diego Based , Halozyme Therapeutics , Eclipse Therapeutics , சான் டியாகோ , ஒன்றுபட்டது மாநிலங்களில் , ரோச் ஜெநிஂடெக் , கெவன் ஷோகாட் , ஜொனாதன் லிம் , சான் டியாகோ அடிப்படையிலானது , கிரகணம் சிகிச்சை ,

BioEclipse Therapeutics Announces First Patient Dosed in Phase 1 Dose-Escalation Clinical Trial of CRX100 in Refractory Solid Tumors


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Mountain View, Calif., March 5, 2021 /PRNewswire/ BioEclipse Therapeutics™ (BioEclipse), a private clinical-stage biopharmaceutical company with a proprietary platform for developing next-generation cancer immunotherapies, announced today the administration of the first dose of CRX100 to a volunteer in the ongoing Phase 1 clinical trial in patients with refractory solid tumors. The trial is a first-in-human study for CRX100, BioEclipse s lead investigational drug candidate, an intravenously delivered, multi-mechanistic therapy designed to target and destroy multiple cancer types and address disease recurrence.
The trial volunteer was administered a single dose of CRX100 at the HonorHealth Research Institute in Scottsdale, Ariz., one of two trial sites participating in a Phase 1, open-label, dose-escalation study exploring the safety, tolerability, and pharmacokinetic (PK) properties of CRX100 in patients with advanced solid tu ....

Pamela Contag , Ron Carozza , Research Associates , Honorhealth Research Institute In Scottsdale , Stanford University , Mountain View , Eclipse Therapeutics , Honorhealth Research Institute , Clinical Operations , Bioeclipse Therapeutics , ரோன் கரோஸ்ஸா , ஆராய்ச்சி கூட்டாளிகள் , மரியாதை ஆராய்ச்சி நிறுவனம் இல் ஸ்காட்ஸ்டேல் , ஸ்டான்போர்ட் பல்கலைக்கழகம் , மலை பார்வை , கிரகணம் சிகிச்சை , மரியாதை ஆராய்ச்சி நிறுவனம் , மருத்துவ செயல்பாடுகள் ,

BioEclipse Initiates Enrollment in Phase 1 Dose-Escalation Clinical Trial for CRX100 at HonorHealth Research Institute


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MOUNTAIN VIEW, Calif., Jan. 19, 2021 /PRNewswire/  BioEclipse Therapeutics™ (BioEclipse), a private clinical-stage biopharmaceutical company with a proprietary platform for developing next-generation cancer immunotherapies, announced today the initiation of patient enrollment at the HonorHealth Research Institute in Scottsdale, Ariz. for a Phase 1 dose-escalation trial to treat refractory solid tumors. The trial marks the first-in-human study of CRX100, an intravenously delivered agent designed to target and destroy multiple cancer types and address disease recurrence.
We are excited to be working with HonorHealth as we advance CRX100 into the clinic, an event that marks a major milestone for our company, stated Pamela Contag, Ph.D., President and CEO of BioEclipse. CRX100 is a single therapeutic designed to attack multiple characteristics of numerous cancer types. With this new approach, BioEclipse is poised to address the ....

United States , Jasgit Sachdev , Pamela Contag , Honorhealth Research Institute In Scottsdale , Johnc Lincoln Health Network , Honorhealth Research Institute On Facebook , Stanford University , Honorhealth Research Institute , Bioeclipse Therapeutics , Gynecological Early Phase Clinical Trials , Principal Investigator , Eclipse Therapeutics , Scottsdale Healthcare , Health Research Institute , ஒன்றுபட்டது மாநிலங்களில் , மரியாதை ஆராய்ச்சி நிறுவனம் இல் ஸ்காட்ஸ்டேல் , மரியாதை ஆராய்ச்சி நிறுவனம் ஆன் முகநூல் , ஸ்டான்போர்ட் பல்கலைக்கழகம் , மரியாதை ஆராய்ச்சி நிறுவனம் , மகளிர் மருத்துவ ஆரம்ப கட்டம் மருத்துவ சோதனைகள் , ப்ரிந்ஸிபல் புலனாய்வாளர் , கிரகணம் சிகிச்சை , ஸ்காட்ஸ்டேல் சுகாதாரம் , ஆரோக்கியம் ஆராய்ச்சி நிறுவனம் ,

BioEclipse to Participate in Biotech Showcase Digital During "J.P. Morgan Week 2021"


During Biotech Showcase Digital, registered conference participants will be able to watch a pre-recorded presentation by BioEclipse. Also, Dr. Contag will host virtual one-on-one meetings with registered investors and pharmaceutical and biotechnology companies via the conference s networking and scheduling platform, partneringONE®, to discuss BioEclipse s business and  highlight recent corporate achievements, as well as anticipated milestones in the clinical program for CRX100. BioEclipse has initiated an open-label, Phase 1 dose-escalation study to evaluate the safety, tolerability, and pharmacokinetic (PK) properties of CRX100 in advanced solid tumors that do not respond to standard of care, including triple-negative breast cancer, colorectal cancer, hepatocellular carcinoma, osteosarcoma, epithelial ovarian cancer, and gastric cancer. ....

Pam Contag , Miriam Miller , Stanford University , Eclipse Therapeutics , Biotech Showcase Digital , Biotech Showcase , Tiberend Strategic , Bioeclipse Therapeutics , மிரியம் மில்லர் , ஸ்டான்போர்ட் பல்கலைக்கழகம் , கிரகணம் சிகிச்சை , பயோடெக் காட்சி பெட்டி டிஜிட்டல் , பயோடெக் காட்சி பெட்டி ,