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Ketogenesis has a protective effect on mitochondria, finds study Ketone bodies are generally an alternative energy source during starvation, but in newborns, ketogenesis is active regardless of nutritional status. In a recent study from Kumamoto University (Japan), researchers analyzed the effects of ketogenesis in mice and found that it has a protective effect on cells by maintaining the function of mitochondria. They expect that this effect can be used in future therapies for protecting mitochondria and organs. Ketones, along with glucose and fatty acids, are metabolites used as energy sources. In particular, ketones are known to be an alternative energy source during periods of fasting or starvation. However, ketogenesis is known to be active in the neonatal period regardless of the number of calories consumed during nursing, and role it plays in newborns is not well understood. ....
WHA’s president outlines plans to improve treatments for patients with hepatitis Danjuma Adda, a Nigerian public health expert, became the president-elect of the World Hepatitis Alliance (WHA) in November last year. He is the first African to hold the position. Having been infected and lost his mother to hepatitis B, Adda s personal experience has fueled his passion and drive for a paradigm shift in fighting the liver disease, which the WHO estimates affects 60 million Africans. In an interview with SciDev.Net, he outlined his plans to increase evidence-based research to improve treatments for patients with hepatitis, and investment commitments by African governments that will drive efforts to eliminate viral hepatitis. ....
New high-performance, safe MRI contrast agent for 3D vascular mapping Heart attack and stroke are the first and second leading causes of death in developed countries, respectively. As the disease often results in sudden death with few special prognostic symptoms, early diagnosis is very important. For this purpose, imaging techniques such as magnetic resonance imaging (MRI) are widely used to identify the narrowing or blockage of blood vessels. In MRI, contrast agents improve the visibility of the structures such as smaller blood vessels within the body. Just as satellites or global positioning systems (GPS) give traffic congestion information, the MRI contrast agents can give accurate information of vascular conditions such as vascular blockage and stenosis. Commonly used products are the gadolinium-based contrast agents. Free gadolinium ions have high toxicity, and thus they must be administered in chelated forms. ....
Women with polycystic ovary syndrome (PCOS) are at a significantly increased risk of contracting COVID-19 than women without the condition, new research led by the University of Birmingham has revealed. ....
Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction fewer than a quarter of sequenced patients. ....