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Ageing impairs critical final egg maturation stage

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IMAGE: Examples of the human oocyte stages used in this study. On the left is an immature GV-stage oocyte recognizable by a visible cell nucleus (white arrow) called germinal vesicle (GV)..
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Credit: Montserrat Barragan/Clinica Eugin
Age may adversely affect women s fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of a human egg cell, according to the findings of a new study published today in the journal
Aging Cell.
Researchers from the Centre for Genomic Regulation (CRG), the Centro Nacional de Análisis Genómico (CNAG-CRG) and Clínica Eugin sequenced the RNA molecules, also known as the transcriptome, within oocytes to understand which genes are affected in their activity by age. They used single-cell sequencing to analyse the transcriptome of 72 individual oocytes from 37 donors between 18 and 43 years of age. ....

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Scientists in California, Texas to study ways to help children receiving heart transplants

American Heart Association
Scientific research teams in California and Texas have been awarded nearly $1.4 million in grants to study ways to improve pediatric heart transplant outcomes.
These first two research awards mark the initial investment of the joint $3 million funding initiative between American Heart Association, the world’s leading voluntary health organization devoted to fighting cardiovascular disease, and Enduring Hearts, a non-profit organization dedicated to funding innovative research aimed at improving the lives of children living with transplanted hearts.
The announcement comes during National Pediatric Transplant Week, April 18-24, 2021. According to Enduring Hearts, more than 450 children undergo a heart transplant in the U.S. each year. Although medical advances have improved over the years, many of these children and their families still face a lifetime of challenges. More than one in four pediatric heart transplants will fail within five year ....

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Global Single Cell Genomics Market Report 2021-2025: Single Cell Genomics Identifying New Forms of Life, Driving Enormous New Research Area with Wide Health Care Applications

Global Single Cell Genomics Market Report 2021-2025: Single Cell Genomics Identifying New Forms of Life, Driving Enormous New Research Area with Wide Health Care Applications
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Labroots Presents its 9th Annual Genetics Virtual Week, to Showcase the Latest Advancements in Genomics, Molecular Diagnostics, and Precision Medicine, April 20-22, 2021

Labroots Presents its 9th Annual Genetics Virtual Week, to Showcase the Latest Advancements in Genomics, Molecular Diagnostics, and Precision Medicine, April 20-22, 2021
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Shaping the future of healthcare, this free 3-day event delivers an in-depth tri-topic agenda including keynotes, panels and speakers to highlight astonishing changes in the healthcare field and the life sciences sector
YORBA LINDA, Calif. (PRWEB)
April 15, 2021
Labroots, the leading scientific social networking website offering premier, interactive virtual events and webinars, continues to deliver on its commitment to empower the scientific community with cutting-edge research and expanded knowledge in genetics and genomics, molecular diagnostics and precision medicine. Revealing enhanced efficiencies in healthcare delivery and improvement in human health, Genetics Virtual Week hosted on April 20-22, offers a virt ....

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MD Anderson researchers recognized by AACR

“Scientists and clinicians in the early phases of their career are crucial to our mission to end cancer and play a central role in driving innovation in all areas of cancer research, prevention, diagnosis and treatment,” said Giulio Draetta, M.D., Ph.D., chief scientific officer at MD Anderson. “We congratulate these junior investigators on receiving such notable recognition from AACR for their high-impact work.”
Navin: Outstanding Achievement in Basic Cancer Research
This prestigious AACR scientific achievement award was established to recognize an early career investigator for achievements in basic cancer research. Navin was selected for his seminal contributions to the understanding of genome evolution and intratumor heterogeneity in breast cancer and for his invention of single-cell DNA sequencing, which has impacted many diverse fields of biology and biomedicine and has directly contributed to the establishment of the single cell genomics field. ....

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