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Spanish scientists identify a mechanism through which dendritic cells improve their antiviral and immunotherapy strategies


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IMAGE: Manuel José Gómez, Ester Marina-Zárate, Almudena Ramiro, Ana Dopazo, Irene Fernández-Delgado, Francisco Sánchez-Madrid and Diego Calzada-Fraile
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Credit: CNIC
Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Professor Francisco Sánchez-Madrid have found that dendritic cells, which initiate specific immune responses, can reprogram their genes to improve their immune response. The results of the study, funded by Fundación la Caixa and published today in
Science Advances, could have important applications in the development of new vaccination and immunotherapy strategies.
Dendritic cells are professional antigen-presenting cells that initiate adaptive or specific immune responses. As described by the research team, dendritic cells capture possible pathogenic agents in different tissues and entry sites, process their components, and transport them to lymph nodes. Here, they establ ....

Investigaciones Cardiovasculares , Irene Fern , Diego Calzada Fraile , Almudenar Ramiro , Science Advances , Diego Calzada , Genomic Unit , Ana Dopazo , ஐரீந் ஃபெர்ன் ,