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IMAGE: Manuel José Gómez, Ester Marina-Zárate, Almudena Ramiro, Ana Dopazo, Irene Fernández-Delgado, Francisco Sánchez-Madrid and Diego Calzada-Fraile view more
Credit: CNIC
Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Professor Francisco Sánchez-Madrid have found that dendritic cells, which initiate specific immune responses, can reprogram their genes to improve their immune response. The results of the study, funded by Fundación la Caixa and published today in
Science Advances, could have important applications in the development of new vaccination and immunotherapy strategies.
Dendritic cells are professional antigen-presenting cells that initiate adaptive or specific immune responses. As described by the research team, dendritic cells capture possible pathogenic agents in different tissues and entry sites, process their components, and transport them to lymph nodes. Here, they establish communication wit