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A new COVID variant that first emerged in India has brought further travel restrictions and concern as it spreads in several countries. The B.1.617 variant, with three sub-lineages, was first detected in India in October 2020 and has multiple concerning mutations that affect how it binds to proteins. Now, as it spreads in the UK, some countries are considering stricter measures for British travellers, with Germany curbing non-essential travel from the country. The World Health Organization (WHO) named B.1.617 a variant of concern in May, meaning it either spreads more rapidly, causes more severe disease or decreases the effectiveness of vaccines or treatments. ....
Tuberculosis (TB), caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb) is the leading cause of death from a single infectious agent world-wide claiming over 1.5 million lives each year. With an increase in resistance to current antibiotics means that novel drugs to kill Mtb are urgently needed. Researchers from the University of Warwick have successfully discovered how Mycobacterium tuberculosis uses an essential sugar to survive in the human body for long time periods; this provides a platform to design new and improved TB drugs and diagnostic agents. Trehalose is one source of energy found in the pathogen’s own cell wall and it appears that ....
The UK announced in December that a more transmissible variant of COVID-19 was spreading in the country, prompting stricter lockdown measures and travel restrictions. Since then, several other variants have emerged in different parts of the world. Viruses often change as they make copies of themselves and these changes are called mutations. The World Health Organization (WHO) defines a variant as a virus that has one or several new mutations . Changes in the coronavirus are not unusual: viruses have more opportunities to mutate as they infect more people but experts have said that SARS-CoV-2 has been slower to change. Here’s what we know about the coronavirus variants in Britain, South Africa, Brazil and California. ....