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Two local developers are planning lofts for the DeWitt-Wharton Manufacturing Company Building and hope to start renovations on the historic building at 1701 12th St. in early 2022. ....
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May 17, 2021 Therapeutic-dose anticoagulation primarily consisting of rivaroxaban (Xarelto; Bayer/Janssen), compared with standard thromboprophylaxis, does not improve outcomes in patients hospitalized with COVID-19 who have elevated D-dimer levels, according to results from the randomized ACTION trial. A “win ratio” analysis indicated that full-dose anticoagulation was no better, and potentially worse, than usual care in terms of a hierarchical composite endpoint of mortality, duration of hospitalization, and duration of oxygen use through 30 days, Renato Lopes, MD, PhD (Duke Clinical Research Institute, Durham, NC), reported over the weekend during the virtual American College of Cardiology 2021 Scientific Session. A composite of thromboembolic events occurred at a numerically but nonsignificantly lower rate in the therapeutic-dose group (7.4% vs 9.9%), although that was offset by a nonsignificant increase in all-cause mortality (11.3% vs 7.6%) and a substantial ....
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Bounded by two Lynchburg residential historical districts, on the periphery of downtown, the DeWitt-Wharton Manufacturing Company Building towers over the neighboring residences. The building, a snapshot of Lynchburgâs early textile manufacturing, is the cityâs newest addition to the Virginia Landmarks Register. Located at 1701 12th Street, the four-story brick building is emblematic of the rise of a thriving textile industry in Lynchburg during the early 20th century. Designed by prolific Lynchburg architect Edward Frye, who had a hand in many of the Victorian-inspired homes along Rivermont Avenue, this is one of the only examples of his work on an industrial building. ....