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Sunshine Biopharma and University of Georgia – SBFM-PL4 and Two Compounds


Sunshine Biopharma and University of Georgia – SBFM-PL4 and Two Compounds
February 9, 2021
Types: Inhibitors of coronavirus main protease (Mpro), an enzyme that is essential for viral replication.
2021 Status: Sunshine Bio said February 10 that it launched a transgenic mice study of its COVID-19 treatment that has been under development since May 2020. The mice being used in the study have been genetically engineered to express the human angiotensin-converting enzyme 2 (hACE2) transmembrane protein in their lungs making them susceptible to lethal infection by SARS-CoV-2. The SARSCoV-2 virus uses the hACE2 receptor to gain entry into human cells to replicate. Sunshine said the goal of the study is to determine if its protease inhibitors will protect the hACE2- transgenic mice from disease progression and death following infection with SARS-CoV-2. ....

Scottd Pegan , College Of Pharmacy , Biomedical Sciences , University Of Georgia , Sunshine Biopharma , Drug Discovery , Interim Associate Head , கல்லூரி ஆஃப் மருந்தகம் , உயிர் மருத்துவ அறிவியல் , பல்கலைக்கழகம் ஆஃப் ஜார்ஜியா , மருந்து கண்டுபிடிப்பு , இடைக்கால இணை தலை ,