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A research team led by a biomedical scientist at the University of California, Riverside, has discovered a new immune pathway in chickens that viruses ....
Sunshine Biopharma and University of Georgia â SBFM-PL4 and Two Compounds February 9, 2021 Types: Inhibitors of coronavirus main protease (Mpro), an enzyme that is essential for viral replication. 2021 Status: Sunshine Bio said February 10 that it launched a transgenic mice study of its COVID-19 treatment that has been under development since May 2020. The mice being used in the study have been genetically engineered to express the human angiotensin-converting enzyme 2 (hACE2) transmembrane protein in their lungs making them susceptible to lethal infection by SARS-CoV-2. The SARSCoV-2 virus uses the hACE2 receptor to gain entry into human cells to replicate. Sunshine said the goal of the study is to determine if its protease inhibitors will protect the hACE2- transgenic mice from disease progression and death following infection with SARS-CoV-2. ....